Patents Assigned to Chiesi Farmaceutici S.p.A.
  • 1-phenyl-2-pyridinyl alkyl alcohol compounds as phosphodiesterase inhibitors
    Patent number: 9056176
    Abstract: 1-Phenyl-2-pyridinyl alkyl alcohol compounds are effective as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and may be used to prevent and/or treat certain diseases or conditions.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: June 16, 2015
    Assignee: CHIESI FARMACEUTICI S.P.A.
    Inventors: Gabriele Amari, Elisabetta Armani, Maurizio Delcanale
  • HETEROARYL DERIVATIVES
    Publication number: 20150158858
    Abstract: Compounds of formula (I) described herein are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for the prevention and/or treatment of diseases of the respiratory tract characterized by airway obstruction.
    Type: Application
    Filed: December 4, 2014
    Publication date: June 11, 2015
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Gabriele AMARI, Elisabetta ARMANI, Eleonora GHIDINI, Charles BAKER-GLENN, Hervé VAN DE POËL, Ben WHITTAKER
  • BENZHYDRYL DERIVATIVES
    Publication number: 20150158857
    Abstract: Compounds having a benzhydryl structure represented by formula (I) described herein are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for treating diseases of the respiratory tract.
    Type: Application
    Filed: December 4, 2014
    Publication date: June 11, 2015
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Gabriele AMARI, Elisabetta Armani, Carmelida Capaldi, Renato De Fanti, Mauro Riccaboni, Charles Baker-Glenn, Hervé Van De Poël
  • COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY
    Publication number: 20150139916
    Abstract: Compounds of formula (I) defined herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.
    Type: Application
    Filed: January 30, 2015
    Publication date: May 21, 2015
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Fabio RANCATI, Ian Linney, Chris Knight, Wolfgang Schmidt
  • COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY
    Publication number: 20150133491
    Abstract: Compounds of formula (I) described herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.
    Type: Application
    Filed: January 23, 2015
    Publication date: May 14, 2015
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Fabio RANCATI, Ian LINNEY
  • Kinase inhibitors
    Patent number: 9029373
    Abstract: Compounds of formula (I): wherein R2, W, A, Y, and R1 are as defined in the specification, and pharmaceutically acceptable salts thereof, are p38 MAPK inhibitors, and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: May 12, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Monique Bodil Van Niel, Nicholas Charles Ray, Andrew Peter Cridland, Christopher Hurley, Lilian Alcaraz, Terry Aaron Panchal, Andrew Stephen Robert Jennings, Elisabetta Armani
  • Compounds
    Patent number: 9023855
    Abstract: Compounds of formula (I): are useful as inhibitors of human neutrophil elastase.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: May 5, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Toby Jonathan Blench, Christine Edwards, Robert Andrew Heald, Janusz Jozef Kulagowski, Jonathan Mark Sutton, Carmelida Capaldi
  • Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors
    Patent number: 9024027
    Abstract: Compounds, pyridine N-oxides, and pharmaceutically acceptable salts of formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and for preventing and/or treating diseases of the respiratory tract characterized by airway obstruction, such as asthma or COPD.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: May 5, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Elisabetta Armani, Gabriele Amari, Carmelida Capaldi, Laura Carzaniga, Elena La Porta, Matilde Guala
  • PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR
    Publication number: 20150111931
    Abstract: The present invention relates to a process for the preparation of compounds endowed with phosphodiesterase (PDE4) inhibitory activity having formula (I). The invention also relates to the process for the isolation by crystallization of the compound (I) and to its use for the preparation of pharmaceutical compositions for inhalation in combination with suitable carriers or vehicles. The present invention also relates to solvates and crystal forms of a compound of formula (I). The synthesized product is suitable for use in pharmaceutical applications for instance in the treatment of respiratory diseases.
    Type: Application
    Filed: October 17, 2014
    Publication date: April 23, 2015
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Alessandro FALCHI, Emilio LUTERO, Emanuele FERRARI, Fausto PIVETTI, Rocco BUSSOLATI, Edoardo MARIANI, Orsola VECCHI, Erhard BAPPERT, Caterina VENTRICI
  • Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity
    Patent number: 9012644
    Abstract: Compounds of formula (I) act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for treating and/or preventing broncho-obstructive and inflammatory diseases.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: April 21, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Fabio Rancati, Andrea Rizzi, Ian Linney, Wesley Blackaby, Chris Knight
  • PROCESS FOR PREPARING PHARMACEUTICAL FORMULATIONS FOR INHALATION COMPRISING A HIGH-DOSAGE STRENGTH ACTIVE INGREDIENT
    Publication number: 20150104516
    Abstract: Cohesive high-dosage strength micronized active ingredients may be dispersed in dry powder formulations for inhalation comprising carrier particles, by use of the apparatus described herein.
    Type: Application
    Filed: September 11, 2014
    Publication date: April 16, 2015
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Claudio CAFIERO, Federico TOSINI
  • Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors
    Patent number: 9000177
    Abstract: Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: April 7, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Maurizio Delcanale, Elisabetta Armani, Gabriele Amari
  • Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity
    Patent number: 8987299
    Abstract: Compounds of formula (I) described herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: March 24, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Fabio Rancati, Ian Linney
  • KINASE INHIBITORS
    Publication number: 20150080375
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof: wherein R2, W, A, Y and R1 are as defined in the specification, are p38 MAPK inhibitors, and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
    Type: Application
    Filed: October 14, 2014
    Publication date: March 19, 2015
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Monique Bodil Van Niel, Nicholas Charles Ray, Lilian Alcaraz, Terry Aaron Panchal, Andrew Stephen Robert Jennings, Elisabetta Armani, Andrew Peter Cridland, Christopher Hurley
  • Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity
    Patent number: 8980913
    Abstract: Compounds of formula (I) defined herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: March 17, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Fabio Rancati, Ian Linney, Chris Knight, Wolfgang Schmidt
  • Process for preparing carrier particles for dry powders for inhalation
    Patent number: 8974831
    Abstract: Carrier particles in which at least 60% of the surface is coated with magnesium stearate are useful for preparing dry powder formulations for inhalation.
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: March 10, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Rossella Musa, Daniela Cocconi, Alain Chamayou, Laurence Galet
  • 1-PHENYLALKANECARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND MULTIPLE SCLEROSIS
    Publication number: 20150065567
    Abstract: Administration of certain 1-phenylalkanecarboxylic acid derivatives is useful for treating, preventing and/or reducing the risk of developing Alzheimer's Disease and multiple sclerosis.
    Type: Application
    Filed: August 15, 2014
    Publication date: March 5, 2015
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Bruno Imbimbo, Marina Pizzi, Daniel Chain
  • ISOXAZOLIDINE DERIVATIVES
    Publication number: 20150057257
    Abstract: Anti-inflammatory and antiallergic compounds of the glucocorticosteroid series, according to formula (I) according to formula (I) defined herein are useful for treating diseases of the respiratory tract characterized by airway obstruction.
    Type: Application
    Filed: November 10, 2014
    Publication date: February 26, 2015
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Eleonora GHIDINI, Andrea RIZZI
  • KINASE INHIBITORS
    Publication number: 20150057273
    Abstract: Disclosed are compounds having [1,2,4]triazolo[4,3-a]pyridine groups and pharmaceutically acceptable salts thereof. The compounds are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
    Type: Application
    Filed: December 9, 2011
    Publication date: February 26, 2015
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Harry Finch, Monique Bodil Van Niel, Chi-Kit Woo
  • Tetrahydropyrrolopyrimidinediones and their use in therapy
    Patent number: 8957082
    Abstract: The subject invention provides compounds of formula (I): Including monomers and multimers thereof that are inhibitors of human neutrophil elastase (HNE) activity and are useful in the treatment of diseases or conditions in which HNE plays a part.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: February 17, 2015
    Assignee: Chiesi Farmaceutici S.p.A
    Inventors: Nicholas Charles Ray, Harry Finch, Christine Edwards, Elizabeth O'Connor