Patents Assigned to Children's Cancer Institute Australia for Medical Research
  • Small molecules inhibiting oncoprotein Myc
    Patent number: 9387213
    Abstract: Pharmaceutical compositions including a Myc inhibitor are provided. Also provided are methods for treating cancer including administration of compounds that inhibit oncoprotein Myc.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: July 12, 2016
    Assignees: Health Research, Inc., Panacela Labs, Inc., Children's Cancer Institute Australia for Medical Research
    Inventors: Andrei Gudkov, Mikhail Nikiforov, Catherine Burkhart, Michelle Haber, Murray Norris
  • Small molecule inhibitors of MRP1 and other multidrug transporters
    Patent number: 8318724
    Abstract: A method of potentiating the activity of a therapeutic drug, like a chemotherapeutic drug or an antibiotic, in a cell or tissue, by inhibiting the efflux capability of a multidrug transporter are disclosed. The method is useful in the treatment of a cancer by sensitizing tumor cells to a chemotherapeutic agent. Compounds capable of inhibiting an efflux capability of a multidrug transporter also are disclosed.
    Type: Grant
    Filed: May 13, 2005
    Date of Patent: November 27, 2012
    Assignees: The Cleveland Clinic Foundation, Children's Cancer Institute Australia for Medical Research
    Inventors: Andrei Gudkov, Michelle Haber, Murray Norris
  • Determining drug resistance
    Publication number: 20070112175
    Abstract: A method for inducing in a cell a resistance to an anti-microtubule agent comprising the step of providing in a cell, a nucleic acid molecule that encodes a mutant actin, or providing in a cell, a mutant actin.
    Type: Application
    Filed: March 18, 2004
    Publication date: May 17, 2007
    Applicant: Children's Cancer Institute Australia for Medical Research
    Inventor: Maria Kavallaris