Patents Assigned to CHILDREN'S HOSPITAL OF FUDAN UNIVERSITY
  • Publication number: 20240092884
    Abstract: An anti-ANGPTL3 antibody or an antigen-binding fragment thereof. The present invention provides an anti-ANGPTL3 antibody or an antigen-binding fragment thereof, wherein a heavy chain variable region includes complementarity determining regions (CDRs), including CDR-H1 having an amino acid sequence as set forth in SEQ ID No. 1, CDR-H2 having an amino acid sequence as set forth in SEQ ID No. 2, and CDR-H3 having an amino acid sequence as set forth in SEQ ID No. 3; and the CDRs of a light chain variable region includes CDR-L1 having an amino acid sequence as set forth in SEQ ID No. 4, CDR-L2 having an amino acid sequence as set forth in SEQ ID No. 5, and CDR-L3 having an amino acid sequence as set forth in SEQ ID No. 6. The antibody or the antigen-binding fragment thereof provided in the present invention can specifically recognize ANGPTL3.
    Type: Application
    Filed: March 30, 2021
    Publication date: March 21, 2024
    Applicant: CHILDREN'S HOSPITAL OF FUDAN UNIVERSITY
    Inventors: HONG XU, QIAN SHEN, JIA RAO, YIHUI ZHAI, LI SUN, HAIMEI LIU, QIANYING LV, XINLI HAN
  • Publication number: 20230008463
    Abstract: The present disclosure discloses an intelligent screening algorithm and automatic upgrading system for congenital heart diseases of newborns based on big data. The key point of the technical solution is as follows: The intelligent screening algorithm and automatic upgrading system includes a heart sound data module, a heart sound data processing module, a blood oxygen data module, a blood oxygen data processing module, a network upgrading module, a database, an intelligent analysis module and a congenital heart disease evaluation module; the heart sound data module is configured to acquire various data of heart sounds of a newborn for centralized processing; and the heart sound data processing module is configured to process the data in the heart sound data module and extract heart sound feature parameters.
    Type: Application
    Filed: September 21, 2022
    Publication date: January 12, 2023
    Applicant: Children's Hospital of Fudan University
    Inventors: Guoying Huang, Xiaojing Hu, Chunyu Wang, Chengqiang Zhang
  • Patent number: 10518983
    Abstract: The present invention discloses a highly efficient and intelligent drug and parenteral nutrition product automatic collation and reversion device, which comprises a feeding conveyor belt, a discharging conveyor belt, a returning conveyer belt and computer; and in the junction of the feeding conveyor belt, the discharging conveyor belt and the returning conveyer belt is provided an inspection module. In the present invention, drug dispatch is configured to be done just as a production line, by providing a weighing scale to measure the weight of drugs, and four cameras to assist in identifying drugs to check whether correct drugs are dispatched, and in case that any errors detected, the wrong drugs will be sent back to the original position for inspection, which improves efficiency and accuracy of drug dispatch and reduces manpower cost.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: December 31, 2019
    Assignee: CHILDREN'S HOSPITAL OF FUDAN UNIVERSITY
    Inventors: Zhiping Li, Jinmiao Lu, Qin Li, Guangfei Wang, Yidie Huang, Xiaoxia Li