Patents Assigned to Children's Hospital of Pittsburgh
  • OXIDANT SCAVENGERS FOR TREATMENT OF DIABETES OR USE IN TRANSPLANTATION OR INDUCTION OF IMMUNE TOLERANCE
    Publication number: 20080085883
    Abstract: The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method of protecting and/or enhancing viability of cells/tissues/organs during isolation (harvesting), preservation, expansion and/or transplantation. In yet another embodiment, the present invention relates to a method of inducing immune tolerance. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: September 19, 2007
    Publication date: April 10, 2008
    Applicants: AEOLUS SCIENCES, INC., National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Children's Hospital of Pittsburgh
    Inventors: Jon PIGANELLI, Kathryn HASKINS, Sonia FLORES, James CRAPO, Brian DAY, Ronald GILL, Richard GAMMANS, Manisha PATEL