Patents Assigned to Children's Hospital Research Foundation
  • Patent number: 4624850
    Abstract: This invention provides a live attenuated human rotavirus vaccine and a method for the preparation of such a vaccine. The method overcomes problems experienced hitherto in the growth of human rotaviruses, by the use of larger quantities of inocula at the initial growth stage and subsequent passages.
    Type: Grant
    Filed: February 8, 1985
    Date of Patent: November 25, 1986
    Assignee: Royal Children's Hospital Research Foundation
    Inventors: Manuel J. Albert, Graeme L. Barnes, Ruth F. Bishop
  • Patent number: 4558279
    Abstract: A novel and improved method to detect indirectly a temperature of an object employing nuclear magnetic resonance techniques (NMR). The method involves obtaining an NMR spectrum to determine chemical shift, relaxation times, spin-spin couplings or quadrupole couplings for an element of a compound having at least one conformational isomer wherein the compound is influenced by a temperature of the object. Uniquely, the present invention may detect temperature in the body of an animal. Further, the present invention discloses a novel method to determine and monitor thermal physiological states in an animal as well as determine and monitor thermal states in an object. Because of the unique and advantageous non-invasive, non-destructive and non-ionizing properties, the present invention may be employed in an object or animal continuously.
    Type: Grant
    Filed: March 7, 1983
    Date of Patent: December 10, 1985
    Assignees: University of Cincinnati, Children's Hospital Research Foundation
    Inventors: Jerome L. Ackerman, Leland C. Clark, Jr., Stephen R. Thomas