Abstract: Substantially purified Eimeria maxima gametocytes have been prepared and methods for their preparations are disclosed. A proteinaceous extract derived from the gametocytes comprises at least nine proteins of varying molecular weights. Vaccines for conferring upon a chicken immunity against infection comprise an effective immunizing amount of gametocyte extract or antigenic protein, and a carrier.
Type:
Grant
Filed:
November 2, 1995
Date of Patent:
August 3, 1999
Assignee:
Chilwalner
Inventors:
Michael Wallach, Thea Pugatsch, David Mencher
Abstract: This invention provides a method of reducing the output of Eimeria oocysts from a newborn chick which comprises administering to a laying hen at a suitable time prior to the hen laying a fertilized egg an amount of native or recombinant antigenic protein present in gametocytes of the Eimeria spp. effective to induce in the hen an immune response conferring protection via maternal immunity against infection or transmission by the Eimeria spp. in the offspring chick.
Type:
Grant
Filed:
August 17, 1993
Date of Patent:
March 5, 1996
Assignee:
Chilwalner
Inventors:
Michael Wallach, Thea Pugatsch, David Mencher