Patents Assigned to Chiros Ltd.
  • Process for preparing a single enantiomer of a lactam using lactamase
    Patent number: 5284769
    Abstract: Lactams of 1-amino-3-carboxylic acid cyclic compounds are produced in enantiomeric form, together with an enantiomer of the corresponding ring-opened amino-acid or ester, by reaction of the racemic lactam with a novel lactamase. The products are useful in the synthesis of chiral carbocyclic nucleotides.
    Type: Grant
    Filed: May 20, 1993
    Date of Patent: February 8, 1994
    Assignee: Chiros Ltd.
    Inventors: Christopher T. Evans, Stanley M. Roberts