Abstract: Intermediate compounds, including 2-(t-butyldimethylsilyloxymethyl)-3,4-[(dimethylmethylene)dioxy]-5-hydroxy-tricyclo[5.2.1.02,6]dec-8-ene, which are useful for the synthesis of neplanocin A having strong antitumor activity. Improved processes for the preparation of neplanocin A, starting from optically active 2-hydroxymethyl-5-hydroxy-tricyclo[5.2.1.02,6]deca-3,8-diene and via a key step comprising a retro-Diels-Alder reaction of the above intermediate.
Abstract: A conventional silsesquioxane derivative has the problems that the functional groups are restricted and the chemical structure is not readily controlled and that it is expensive. The present inventors have developed a process for producing a silsesquioxane derivative at a high yield by a simple process in order to solve such problems. The novel silsesquioxane derivative according to the present invention is controlled in a structure thereof and has a functional group, which is excellent in reactivity with a target compound, to be modified. The present invention relates to a production process for a silsesquioxane derivative represented by Formula (2), characterized by using a silicon compound represented by Formula (1).
Type:
Grant
Filed:
September 15, 2003
Date of Patent:
May 30, 2006
Assignee:
Chisso Corporation
Inventors:
Kenya Ito, Mikio Yamahiro, Kenichi Watanabe
Abstract: This invention provides to a novel pharmaceutical preparation for the treatment of gynecological diseases. The pharmaceutical preparation according to the invention comprises a therapeutic drug for the intrauterine, intravaginal or intrapelvic administration, or for the administration into the ovarian endometrioma, and a biodegradable polymer comprising a chemically modified hyaluronic acid or a salt thereof prepared by O-acylating, alkoxylating or crosslinking a complex of hyaluronic acid or a salt thereof and a cationic compound in a nonaqueous solvent. The preparation of the invention is preferably administered intrauterine, intravaginal, intrapelvic, and intratumor cavity.
Type:
Grant
Filed:
March 28, 2002
Date of Patent:
May 9, 2006
Assignees:
Chisso Corporation
Inventors:
Nobuhiko Yui, Kouichi Murakami, Tooru Ooya, Ikuo Sato
Abstract: A filter cartridge formed by winding, in a twill construction, a band-shaped unwoven cloth, which contains thermoplastic fibers and at least a part of its fiber intersections are stuck thereon, so that a cylindrical shape can be obtained, wherein 1. two types of filtrating layers are used, 2. unwoven cloth having opening hole parts is used, 3. an end face seal part is provided on both end parts of the cartridge, 4. unwoven cloth having a tongue piece part is used, or 5. two or more pieced of unwoven cloth are wound simultaneously, whereby those characteristic of the filter cartridge such as liquid permeability, filterable life, and stability of filtration accuracy can be kept in balance with each other.
Abstract: The present invention provides metallocene compounds which exhibit high polymerization activity for production of highly stereoregular polymers, as well as a production process for olefin polymers which employs olefin polymerization catalysts containing the compounds, and olefin polymers obtained by the production process.
Abstract: A filter cartridge comprising a strip, long fiber non-woven fabric which comprises a thermoplastic fiber and in which at least a part of fiber intersections is adhered, which is wound around a perforated cylinder in a twill form, has made it possible to obtain a cylindrical filter cartridge which is excellent in a liquid-passing property, a filter life and a stability in a filtering accuracy. The thermoplastic fiber constituting the above long fiber non-woven fabric is particularly preferably a thermally adhesive composite fiber comprising a low melting point resin and a high melting point resin and having a melting point difference of 10° C. or more between those of both resins.
Abstract: The PSQ silsesquioxane derivative of the invention is represented by Formula (1), and it may be utilized as additives to ordinary organic polymers for improving the flame retardancy, heat resistance, weather resistance, light resistance, electric insulating property, surface property, hardness, mechanical strength and chemical resistance thereof. In Formula (1), R is hydrogen, alkyl, aryl or arylalkyl; at least one Y is a group represented by Formula (2) and the other Y is hydrogen; in Formula (2), R1 and R2 are a group independently defined similarly to R; and Z is preferably a functional group, or a group having a functional group.
Abstract: A pleated composite fiber net formed of heat-adhesive composite fibers having a fineness of 200 to 2,500 dtex serving as warps and wefts in an opening size of strand of 0.5 to 5 mm, and heat-adhered at the intersections of said composite fibers; wherein the adhesive strength of the heat-adhered portions is 20 cN or higher.
Abstract: Metallocene compounds represented by the following general formula (1): YqKLMX2??(1) wherein M, Y, q, L and X are each as defined in the Specification.
Abstract: A microorganism culture medium comprising a derivative A? of a chromogen A, and a chromogen B, where the chromogen A is a chromogen being oxidized to a colorant, and the chromogen B is a chromogen being reduced to a colorant. The derivative A? acts as a substrate of an enzyme generated when a microorganism is growing, and is then converted to the chromogen A, and the derivative A? and the chromogen B are substantially not colored in the culture medium unless a microorganism is inoculated.
Abstract: An electro-chargeable fiber includes a thermoplastic resin fiber having a nonionic fiber finish containing at least one major component selected from the group consisting of (a) at least one sorbitan fatty acid ester having formula (I) or formula (II) and (b) polyoxyalkylene alkyl ether having formula (III), wherein the nonionic fiber finish is present in an amount of 0.01-1.
Type:
Application
Filed:
May 17, 2005
Publication date:
December 8, 2005
Applicants:
CHISSO CORPORATION, CHISSO POLYPRO FIBER COMPANY LIMITED
Abstract: An object of the present invention is to provide a varnish composition which can achieve totally and with good balance the improvement in various properties including electrical properties such as residual charge, a voltage holding ratio and image sticking, a pre-tilt angle, coating property, alignment property, and so on, which are desired for a liquid crystal aligning film formed. The varnish composition comprises polymer ingredients containing polyamic acid B represented by formula (1), polyamic acid A represented by formula (2) having a side chain of not less than 3 carbon atoms and N-substituted polyamide represented by formula (3), and a solvent for dissolving the polymer ingredients. The varnish composition contains 0.
Abstract: Provided are polyimide and a thin film thereof which have a three-dimensional structure and therefore are excellent in a mechanical strength and a heat resistance as compared with those of conventional linear polyimide. The polyimide is obtained from a salt of multifunctional amine represented by Formula (1): (wherein A represents a tetravalent organic group, and n represents an integer of 0 to 3) and tetracarboxylic diester represented by Formula (2): (wherein B represents a tetravalent organic group having 1 to 20 carbon atoms, and R1 and R2 each represent independently an alkyl group having 1 to 5 carbon atoms).
Abstract: The present invention provides a liquid crystal display element having an adequate pre-tilt angle for preventing the reverse domain, as well as excellent electrical properties by preparation of the polyamic acid composition for the liquid crystal display element comprises a polyamic acid A that excels in electrical properties and a polyamic acid B that has side chains, mixed in the ratio A/B of 50/50 to 95/5 (by weight).
Type:
Grant
Filed:
December 8, 1998
Date of Patent:
September 20, 2005
Assignee:
Chisso Corporation
Inventors:
Satoshi Tanioka, Shizuo Murata, Itsuo Shimizu, Kazumi Ito
Abstract: A thrombin derivative having a lowered fibrinogen activity, a process for producing thereof, an anhydrothrombin derivative having a lowered fibrinogen activity, and a process for producing thereof are provided. This invention is to provide a thrombin derivative formed by modifying carboxyl group(s) of the thrombin and an anhydrothrombin derivative formed by modifying carboxyl group(s) of the anhydrothrombin. The thrombin derivative can be utilized as a composition for inducing platelet aggregation and further as a reagent of specific aggregation for clinical testing and the like. By affinity chromatography using carboxyl group(s) bound with anhydrothrombin as a ligand, it is made possible to carry out necessary purification with high selectivity relative to the blood coagulation factor VIII.
Abstract: A liquid crystal composition comprising a first component consisting of at least one compound selected from a group of compounds represented by Formula (I) and a second component consisting of at least one compound selected from a group of compounds represented by Formulas (II-1) to (II-8): in which each symbols of Formula (I) are defined in the specification and Formulas (II-1) to (II-8) and their symbols are also defined in the specification.
Abstract: A cyclic tertiary amine compound represented by a formula (1) and an organic luminescent device are disclosed. Use of the cyclic tertiary amine compound as a hole transport material, a hole injection material or an organic electroluminescent material can provide organic EL devices having high luminous efficiency and a long service life.
Abstract: A liquid crystal composition having a negative dielectric anisotropy, containing at least one compound selected from the group of compounds represented by Formulas (1-1), (1-2), (1-3) and (1-4) as a first component: wherein R5 is alkyl or alkenyl; R2 is alkyl or alkoxy; A5 is 1,4-phenylene or 2-fluoro-1,4-phenylene; and A6 is 1,4-phenylene, 2-fluoro-1,4-phenylene or 2,3-difluoro-1,4-phenylene.
Abstract: A liquid crystal composition containing at least one compound selected from compounds of formula (1) and formula (2) as a first component, at least one compound selected from compounds of formula (3) as a second component, and at least one compound selected from compounds of formula (4) as a third component: wherein R1 is alkyl; R2 is alkyl or alkenyl; Z1 and Z2 are independently a single bond or —(CH2)2—; X1 is hydrogen or fluorine; and Y1 is fluorine or —OCF3. Also provided is a liquid crystal display element containing the composition.
Abstract: A charge transporting material, a light emitting material and an organic electroluminescent device having high efficiency using a specified diazapentacene derivative represented by the following general formula (1): (in the general formula (1), R1 to R10 each represents independently a hydrogen atom, a halogen atom, an alkyl group of 1 to 6 carbon atoms, an alkoxy group, a substituted or not-substituted amino group, an aryl group or a heterocyclic group, in which the substituted or not-substituted aryl group or heterocyclic group, when they are adjacent with each other, may be of a structure condensed to each other, X1 and X2 each represents independently an oxygen atom or a sulfur atom, and Y1 and Y2 each represents independently a substituted or not-substituted alkyl group of 1 to 6 carbon atoms, an aryl group or a heterocyclic group).