Patents Assigned to Cho-A Pharm Co., Ltd.
  • Patent number: 9738694
    Abstract: The present invention relates to a porcine alpha-S1-casein gene, a porcine alpha-S1-casein gene promoter, an expression comprising the same promoter, and a method for the production of a target protein using the same expression vector. The promoter of the present invention facilitates the mammary gland-specific expression of the target protein. Accordingly, an animal transformed with the promoter secretes the target protein in milk at high concentration, and thus can be advantageously used for the production of useful proteins.
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: August 22, 2017
    Assignee: CHO-A PHARM. CO., LTD.
    Inventors: Myeong Goo Yeo, Sung-Jo Kang, Jong Deok Ahn
  • Patent number: 8420388
    Abstract: The present invention provides a porcine beta-casein gene, a porcine beta-casein gene promoter, an expression vector comprising the same promoter, and a method for the production of a target protein using the same expression vector. The promoter of the present invention facilitates mammary gland-specific expression of the target protein and therefore can be useful for high-concentration production of beneficial proteins in milk.
    Type: Grant
    Filed: December 31, 2008
    Date of Patent: April 16, 2013
    Assignee: Cho-A Pharm. Co., Ltd.
    Inventors: Jin Hoi Kim, Myeong Goo Yeo, Sung-Jo Kang, Jong Deok Ahn
  • Patent number: 7416886
    Abstract: The present invention relates to a porcine uroplakin II gene promoter, an expression vector containing the promoter, and a method for producing useful proteins using the vector. The promoter of the present invention promotes the bladder-specific expression of a target protein at high efficiency. An animal, which was transformed using the inventive promoter so as to express the target protein, secretes the target protein in its urine at high concentration, and the protein thus produced shows a superior physiological activity to that of the same kind of the existing protein. As a result, the inventive promoter, the expression vector and transgenic animal using the promoter, can be advantageously used in the production field of useful proteins that are medicinally valuable.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: August 26, 2008
    Assignee: Cho-A Pharm Co., Ltd.
    Inventor: Jin-Hoi Kim