Abstract: The invention relates to a recombinant protein used for immunoprophylaxis of human Helicobacter pylori infection and a degradable slow-releasing microsphere-encapsulated oral vaccine preparation prepared from the same, and the preparation method thereof. Said recombinant protein is composed of A2 subunit and B subunit of the LT of enterotoxigenic Escherichia coli and urease B subunit. The vaccine provided in the invention used in human Helicobacter pylori infection is safe and effective and convenient for oral intake.
Type:
Application
Filed:
September 5, 2007
Publication date:
July 14, 2011
Applicant:
Chongqing Kang Wei Biotechnology Co. Ltd.
Inventors:
Quanming Zou, Wende Tong, Xuhu Mao, Gang Guo, Dongshui Lu, Chao Wu, Hao Zeng, Yichao Wang, Jun Yang, Weijun Zhang, Kaiyun Liu, Ping Luo