Abstract: A quinoline derivative compound shown in formula (II), a pharmaceutically acceptable salt thereof, and an application of the same in preparing a drug for treating a disease related to a tyrosine kinase inhibitor.
Type:
Grant
Filed:
September 20, 2018
Date of Patent:
November 2, 2021
Assignees:
CHONGQING PHARMACEUTICAL INDUSTRIAL RESEARCH INSTITUTE CO. LTD., YAOPHARMA CO., LTD.
Abstract: Disclosed in the present invention is a crystal form I of Canagliflozin, and an X-ray powder diffraction spectrum of the crystal form I has characteristic diffraction peaks when 2? is at the position of 4.4±0.2°, 8.4±0.2°, 16.8±0.2°, 17.5±0.2°, 18.0±0.2°, and 22.8±0.2°. The crystal form is physically and chemically stable and is suitable for manufacturing of various preparations.
Type:
Application
Filed:
March 27, 2015
Publication date:
November 30, 2017
Applicant:
CHONGQING PHARMACEUTICAL INDUSTRIAL RESEARCH INSTITUTE CO., LTD