Abstract: The present invention provides a crystalline form of dextral oxiracetam. The crystalline form has a diffraction peak when a diffraction angle, 2?, is 17.12±0.2°, 18.88±0.2°, 19.24±0.2°, 21.18±0.2°, 24.88±0.2°. The crystalline form having oxiracetam can promote synthesis of phosphorylcholine and phosphoethanolamine, boosts cerebral metabolism, has a stimulating function on a specific central nervous pathway through a blood-brain barrier, improves the intelligence and memory, has an obvious effect on a memory dysfunction, and has special biologic activity in the field of sedation and the antiepileptic field. The method for preparing the crystalline form is simple and is suitable for industrial production.
Type:
Grant
Filed:
July 7, 2017
Date of Patent:
June 30, 2020
Assignee:
CHONGQING RUNZE PHARMACEUTICAL COMPANY LIMITED
Abstract: The present invention is to provide uses of the L-oxiracetam in preparation of medicines for preventing or treating coma. Experimental results show that L-oxiracetam wake-promoting effects of alcoholism-induced coma is obvious, and D-oxiracetam has basically no effect. The effect of the above wake-promoting effects of L-oxiracetam is 2 times greater than racemic oxiracetam. The wake-promoting effects of L-oxiracetam on trauma or anesthesia-induced coma are both significant.
Type:
Grant
Filed:
April 24, 2012
Date of Patent:
January 3, 2017
Assignee:
CHONGQING RUNZE PHARMACEUTICAL COMPANY LIMITED.
Abstract: A method for preparing a porous tantalum medical implant material, which includes (a) mixing a polyethylene glycol aqueous solution and tantalum powder to form a tantalum slurry, (b) casting the tantalum slurry into an organic foam body through vibrant pressurization, and (c) performing steps of drying, degreasing, vacuum sintering and thermal treatment to obtain the porous tantalum. The solution is a 2-8 wt % polyethylene glycol aqueous solution, the frequency of vibration is 20-80 times/min, the thermal treatment is performed under 10?4-10?3 Pa of vacuity and the temperature is first increased to 800-900° C. at a rate of 10-20° C./min and kept at 800-900° C. for 240-480 minutes, then is decreased to 400° C. at a rate of 2-5° C./min and kept at 400° C. for 120-300 minutes, and is cooled down to room temperature naturally in the furnace.
Type:
Grant
Filed:
September 27, 2012
Date of Patent:
July 7, 2015
Assignee:
CHONGQING RUNZE PHARMACEUTICAL COMPANY LIMITED
Abstract: The present invention is to provide uses of the L-oxiracetam in preparation of medicines for preventing or treating coma. Experimental results show that L-oxiracetam wake-promoting effects of alcoholism-induced coma is obvious, and D-oxiracetam has basically no effect. The effect of the above wake-promoting effects of L-oxiracetam is 2 times greater than racemic oxiracetam. The wake-promoting effects of L-oxiracetam on trauma or anesthesia-induced coma are both significant.
Type:
Application
Filed:
April 24, 2012
Publication date:
September 18, 2014
Applicant:
Chongqing Runze Pharmaceutical Company Limited