Abstract: Purine derivatives, substituted at the 9-position, are prepared from a chloro substituted purine starting material, first making an alkyl substitution at the 9-position, then forming the desired esterified side chain, reducing this and hydrogenating the resultant diol prior to addition of alkyl carbonyl groups.
Type:
Application
Filed:
November 10, 2005
Publication date:
November 23, 2006
Applicants:
Arrow International Limited, Chongqing Shenghuaxi Pharmaceutical Co. Ltd.