Patents Assigned to CHORDATE MEDICAL AB
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Publication number: 20230000716Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: ApplicationFiled: September 12, 2022Publication date: January 5, 2023Applicant: CHORDATE MEDICAL ABInventors: Jan-Erik JUTO, William HOLM, Fredrik JUTO
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Patent number: 11452666Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: GrantFiled: July 24, 2020Date of Patent: September 27, 2022Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, William Holm, Fredrik Juto
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Publication number: 20200405571Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: ApplicationFiled: July 24, 2020Publication date: December 31, 2020Applicant: CHORDATE MEDICAL ABInventors: Jan-Erik JUTO, William HOLM, Fredrik JUTO
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Patent number: 10772792Abstract: A device is provided for vibrational stimulation of body tissue in body cavities which are difficult to access, particularly in the nasal cavity. The device includes an expandable stimulation member, which can be introduced via a body opening into a body cavity. In an expanded state of the device, the stimulation member abuts against the body tissue within the body cavity. To accomplish vibrational stimulation, the stimulation member is brought to vibrate at a frequency of 48-70 Hz within the body cavity. A method is also provided for vibrational stimulation of body tissue in a body cavity, particularly in the nasal cavity of a patient.Type: GrantFiled: December 22, 2017Date of Patent: September 15, 2020Assignee: CHORDATE MEDICAL ABInventor: Jan-Erik Juto
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Patent number: 10758446Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: GrantFiled: January 18, 2017Date of Patent: September 1, 2020Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, William Holm, Fredrik Juto
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Publication number: 20180133098Abstract: A device is provided for vibrational stimulation of body tissue in body cavities which are difficult to access, particularly in the nasal cavity. The device includes an expandable stimulation member, which can be introduced via a body opening into a body cavity. In an expanded state of the device, the stimulation member abuts against the body tissue within the body cavity. To accomplish vibrational stimulation, the stimulation member is brought to vibrate at a frequency of 48-70 Hz within the body cavity. A method is also provided for vibrational stimulation of body tissue in a body cavity, particularly in the nasal cavity of a patient.Type: ApplicationFiled: December 22, 2017Publication date: May 17, 2018Applicant: CHORDATE MEDICAL ABInventor: Jan-Erik JUTO
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Patent number: 9895279Abstract: A method for stimulating the hypothalamus in a human subject is provided. The method includes the step of imparting vibrations to a posterior part of a nasal cavity of the human subject by a device for stimulation of the hypothalamus, which includes an expandable stimulation member arranged to stimulate hypothalamic activity.Type: GrantFiled: December 14, 2012Date of Patent: February 20, 2018Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, Fredrik Juto
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Patent number: 9849062Abstract: A device is provided for vibrational stimulation of body tissue in body cavities which are difficult to access, particularly in the nasal cavity. The device includes an expandable stimulation member, which can be introduced via a body opening into a body cavity. In an expanded state of the device, the stimulation means abuts against the body tissue within the body cavity. To accomplish vibrational stimulation, the stimulation member is brought to vibrate at a frequency of 48-70 Hz within the body cavity. A method is also provided for vibrational stimulation of body tissue in a body cavity, particularly in the nasal cavity of a patient.Type: GrantFiled: May 16, 2008Date of Patent: December 26, 2017Assignee: CHORDATE MEDICAL ABInventor: Jan-Erik Juto
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Patent number: 9782320Abstract: A method of vibration treatment in at least one nasal cavity of a human subject is provided. The method includes the steps of: inserting a first stimulation member in a first nasal cavity; inserting a second stimulation member in a second nasal cavity; securing the first and second stimulation members such that the stimulation members are in fixed positions within the nasal cavities prior to vibration stimulation; arranging each of the first and second stimulation members to abut against tissue within each of the first and second nasal cavities at a first and second pressure; and imparting vibrations to tissue in at least one of the first and second nasal cavities via at least one of the first and second stimulation members.Type: GrantFiled: December 14, 2012Date of Patent: October 10, 2017Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, Fredrik Juto, Victor Kronestedt, William Holm
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Publication number: 20170128318Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: ApplicationFiled: January 18, 2017Publication date: May 11, 2017Applicant: CHORDATE MEDICAL ABInventors: Jan-Erik JUTO, William HOLM, Fredrik JUTO
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Patent number: 9579247Abstract: A method for treatment of a headache disorder in a human subject is provided. The method includes a) selecting a treatment area in the nasal cavity of the human subject; b) providing a stimulation member arranged for vibration stimulation of the selected treatment area; c) introducing the stimulation member into a nasal cavity of the human subject; d) expanding the stimulation member to exert a pressure on tissue of the selected treatment area; and e) bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area.Type: GrantFiled: December 14, 2012Date of Patent: February 28, 2017Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, William Holm, Fredrik Juto
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Patent number: 9486381Abstract: A method for treating amyotrophic lateral sclerosis (ALS) in a human subject is provided. A first vibration stimulation member is introduced into a posterior part of a first nasal cavity of the human subject. By means of the first vibration stimulation member, vibrations are imparted to the posterior part of the first nasal cavity at frequency in a range of from 60 to 70 Hz. A second vibration simulation member is arranged between the trapezius muscle and the sternocleidomastoid muscle on a first side of the neck of the human subject; and by means of said second vibration stimulation member, vibrations are imparted to the first side of the neck at a frequency in a range of from 30 to 50 Hz.Type: GrantFiled: December 14, 2012Date of Patent: November 8, 2016Assignee: CHORDATE MEDICAL ABInventors: Fredrik Juto, Jan-Erik Juto, William Holm, Viktor Kronestedt
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Patent number: 9474684Abstract: A method for treatment by vibration stimulation of body tissue in a body cavity of a human subject includes providing a stimulation member comprising a dielectric polymer; introducing the stimulation member into a body cavity; expanding the stimulation member to a state such that it abuts the body tissue within the body cavity, and applying a time varying potential to said dielectric polymer to impart vibrations to body tissue in the body cavity.Type: GrantFiled: March 12, 2013Date of Patent: October 25, 2016Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, Fredrik Juto, William Holm
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Patent number: 9451889Abstract: A device for detecting rhinitis in a human subject includes an inflatable member that, in a first state, is configured to be introducible into the nasal cavity of the human subject; an expansion member configured to expand the inflatable member to an expanded, second state within the nasal cavity such that the inflatable member abuts against the tissue of the nasal cavity, and a pressure sensing member configured to measure a pressure exerted on the inflatable member by the tissue of the nasal cavity. A system for detecting rhinitis and methods for analyzing tissue response pressure, detecting rhinitis, predicting the efficacy of a planned rhinitis treatment and evaluating the efficacy of a previous rhinitis treatment are provided.Type: GrantFiled: October 22, 2015Date of Patent: September 27, 2016Assignee: CHORDATE MEDICAL ABInventors: William Holm, Jan-Erik Juto, Fredrik Juto
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Publication number: 20160038046Abstract: A device for detecting rhinitis in a human subject includes an inflatable member that, in a first state, is configured to be introducible into the nasal cavity of the human subject; an expansion member configured to expand the inflatable member to an expanded, second state within the nasal cavity such that the inflatable member abuts against the tissue of the nasal cavity, and a pressure sensing member configured to measure a pressure exerted on the inflatable member by the tissue of the nasal cavity. A system for detecting rhinitis and methods for analyzing tissue response pressure, detecting rhinitis, predicting the efficacy of a planned rhinitis treatment and evaluating the efficacy of a previous rhinitis treatment are provided.Type: ApplicationFiled: October 22, 2015Publication date: February 11, 2016Applicant: CHORDATE MEDICAL ABInventors: William Holm, Jan-Erik JUTO, Fredrik JUTO
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Patent number: 9198618Abstract: A device for detecting rhinitis in a human subject includes an inflatable member that, in a first state, is configured to be introducible into the nasal cavity of the human subject; an expansion member configured to expand the inflatable member to an expanded, second state within the nasal cavity such that the inflatable member abuts against the tissue of the nasal cavity, and a pressure sensing member configured to measure a pressure exerted on the inflatable member by the tissue of the nasal cavity. A system for detecting rhinitis and methods for analyzing tissue response pressure, detecting rhinitis, predicting the efficacy of a planned rhinitis treatment and evaluating the efficacy of a previous rhinitis treatment are provided.Type: GrantFiled: December 14, 2012Date of Patent: December 1, 2015Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, William Holm, Fredrik Juto