Abstract: The invention relates to the use of a substance of the general form (I) to produce an antibacterial and/or antifungal drug, wherein X is a methylene group or a carbonyl group; R1, R2, and R3 are each selected from the group comprising hydrogen, an alkyl group having a chain length of 1-4 carbon atoms, an alkoxy group having a chain length of 1-3 carbon atoms, and a halogen; R4 and R5 are each selected from the group comprising hydrogen and an alkyl group having a chain length of 1-4 carbon atoms; and n=3 to 6.
Type:
Grant
Filed:
June 12, 2015
Date of Patent:
July 4, 2017
Assignee:
CHRISTIAN-ALBRECHTS-UNIVERSITY OF KIEL
Inventors:
Bernd Clement, Franz Furkert, Britta Gerig, Dieter Heber
Abstract: The invention is directed to methods of producing a polypeptide or a variant thereof, wherein the polypeptide or variant thereof is dependent on LIMP-2 for trafficking, localization, stabilization and/or sorting of the polypeptide in the cell. In general, the methods comprise culturing a lysosomal integral membrane protein II (LIMP-2) deficient cell which expresses the polypeptide or the variant thereof under conditions in which the polypeptide or the variant thereof is produced.
Type:
Grant
Filed:
May 9, 2008
Date of Patent:
February 24, 2015
Assignees:
Genzyme Corporation, Biochemical Institute, Christian-Albrechts University Kiel
Inventors:
David J. Reczek, Paul Saftig, Christine T. DeMaria
Abstract: The invention relates to the use of a substance of the general form (I) to produce an antibacterial and/or antifungal drug, wherein X is a methylene group or a carbonyl group; R1, R2, and R3 are each selected from the group comprising hydrogen, an alkyl group having a chain length of 1-4 carbon atoms, an alkoxy group having a chain length of 1-3 carbon atoms, and a halogen; R4 and R5 are each selected from the group comprising hydrogen and an alkyl group having a chain length of 1-4 carbon atoms; and n=3 to 6.
Type:
Application
Filed:
December 21, 2011
Publication date:
October 30, 2014
Applicant:
CHRISTIAN-ALBRECHTS-UNIVERSITY OF KIEL
Inventors:
Franz Furkert, Bernd Clement, Britta Gerig, Dieter Heber
Abstract: A method for producing nanostructures on a substrate, by dripping a solution of nanostructure-forming material in water onto the substrate heated to a temperature above the temperature at which a drop of the solution is initially suspended on a vapor cushion after being applied by dripping onto the substrate, with nanostructures being formed when the drops evaporate.