Patents Assigned to Chromaflow, Inc.
  • Method for charging and discharging chromatography column bed
    Patent number: 5282973
    Abstract: A chromatography column having a media supply and product/buffer inlet assembly positioned at the inlet of a dispersion section at the top of the column and an outlet assembly positioned at the collection section at the bottom of the column for receiving and discharging product components and buffer liquid and for discharging liquefied spent media. The media and product inlet assembly includes a housing having a product and buffer inlet passage including a selectively movable media supply nozzle extending through the housing. The nozzle may be positioned through the dispersion section into the column housing for spraying media in the form of a slurry into the column housing, and may be withdrawn after the media bed is packed. The collection section of the column includes a hollow rod extending through a discharge conduit through which spent media may flow. The rod has a probe at the upper end for entering into the column, a point at the end of the probe being adapted to puncture and chip spent hardened media.
    Type: Grant
    Filed: January 19, 1993
    Date of Patent: February 1, 1994
    Assignee: Chromaflow, Inc.
    Inventor: William H. Mann
  • Apparatus for charging and discharging of chromatography column bed
    Patent number: 5213683
    Abstract: A chromatography column having a media supply and product/buffer inlet assembly positioned at the inlet of a dispersion section at the top of the column and an outlet assembly positioned at the collection section at the bottom of the column for receiving and discharging product components and buffer liquid and for discharging liquefied spent media. The media and product inlet assembly includes a housing having a product and buffer inlet passage including a selectively movable media supply nozzle extending through the housing. The nozzle may be positioned through the dispersion section into the column housing for spraying media in the form of a slurry into the column housing, and may be withdrawn after the media bed is packed. The collection section of the column includes a hollow rod extending through a discharge conduit through which spent media may flow. The rod has a probe at the upper end for entering into the column, a point at the end of the probe being adapted to puncture and chip spent hardened media.
    Type: Grant
    Filed: August 8, 1991
    Date of Patent: May 25, 1993
    Assignee: Chromaflow, Inc.
    Inventor: William H. Mann