Abstract: The invention is generally related to methods of generating plants transformed with novel autonomous mini-chromosomes. Mini-chromosomes with novel compositions and structures are used to transform plants cells which are in turn used to generate the plant. Methods for generating the plant include methods for delivering the mini-chromosome into plant cell to transform the cell, methods for selecting the transformed cell, and methods for isolating plants transformed with the mini-chromosome. Plants generated in the present invention contain novel genes introduced into their genome by integration into existing chromosomes.
Type:
Application
Filed:
September 7, 2006
Publication date:
September 3, 2009
Applicant:
Chromatin Inc.
Inventors:
Helge Zieler, Gary W. Rudgers, Daphne Preuss, Gregory P. Copenhaver, Michael H. Pauly
Abstract: The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
Type:
Application
Filed:
October 31, 2007
Publication date:
August 20, 2009
Applicants:
THE UNIVERSITY OF CHICAGO, CHROMATIN, INC.
Inventors:
Jennifer Mach, Helge Zieler, RongGuan Jin, Kevin Keith, Gregory Copenhaver, Daphne Preuss
Abstract: The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
Type:
Grant
Filed:
January 7, 2005
Date of Patent:
November 25, 2008
Assignees:
Chromatin, Inc., University of Chicago
Inventors:
Jennifer Mach, Helge Zieler, RongGuan Jin, Kevin Keith, Gregory Copenhaver, Daphne Preuss
Abstract: The present invention provides methods of doing business and providing services. For example, methods of increasing the revenue of crops are provided. To this end, the method includes the use of a nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and mini chromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
Type:
Application
Filed:
February 2, 2007
Publication date:
November 20, 2008
Applicants:
CHROMATIN INC., THE UNIVERSITY OF CHICAGO
Inventors:
Jennifer Mach, Helge Zieler, RongGuan Jin, Kevin Keith, Gregory P. Copenhaver, Daphne Preuss
Abstract: The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
Type:
Grant
Filed:
February 2, 2005
Date of Patent:
June 26, 2007
Assignees:
Chromatin, Inc., The University of Chicago
Inventors:
Jennifer Mach, Helge Zieler, James Jin, Kevin Keith, Gregory Copenhaver, Daphne Preuss
Abstract: The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
Type:
Grant
Filed:
February 2, 2005
Date of Patent:
June 5, 2007
Assignees:
Chromatin, Inc., The University of Chicago
Inventors:
Jennifer Mach, Helge Zieler, James Jin, Kevin Keith, Gregory Copenhaver, Daphne Preuss
Abstract: The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
Type:
Grant
Filed:
February 2, 2005
Date of Patent:
June 5, 2007
Assignees:
Chromatin, Inc., The University of Chicago
Inventors:
Jennifer Mach, Helge Zieler, RongGuan Jin, Kevin Keith, Gregory Copenhaver, Daphne Preuss
Abstract: The present invention provides methods of doing business and providing services. For example, methods of increasing the revenue of crops are provided. To this end, the method includes the use of a nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and mini chromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
Type:
Grant
Filed:
June 12, 2002
Date of Patent:
March 20, 2007
Assignees:
Chromatin, Inc., University of Chicago
Inventors:
Gregory P. Copenhaver, Kevin Keith, Daphne Preuss
Abstract: The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
Type:
Application
Filed:
January 7, 2005
Publication date:
December 1, 2005
Applicants:
University of Chicago, Chromatin, Inc.
Inventors:
Jennifer Mach, Helge Zieler, RongGuan Jin, Kevin Keith, Gregory Copenhaver, Daphne Preuss
Abstract: The invention provides efficient methods for the isolation of centromeres from potentially any organism. The methods may comprise the steps of: a) preparing a first sample of genomic DNA from a selected species; b) obtaining a plurality of methylated nucleic acid segments from the genomic DNA; and c) screening the methylated nucleic acid segments to identify a centromere nucleic acid sequence.
Type:
Grant
Filed:
June 22, 2001
Date of Patent:
November 18, 2003
Assignee:
Chromatin, Inc.
Inventors:
Song Luo, Gregory Copenhaver, Kevin Keith, Daphne Preuss