Abstract: Provided herein is a novel epitope that can be used as a tag in methods for rapid and effective characterization, purification, and subcellular localization of polypeptides of interest, which comprise the tag. The tag is specifically recognized by an epitope specific antibody, which can be used to detect, capture, quantify, and/or purify polypeptides of interest that are tagged with the epitope. Also provided is novel epitope specific antibody.
Type:
Application
Filed:
March 11, 2019
Publication date:
February 6, 2020
Applicants:
ChromoTek GmbH, NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen
Inventors:
Ulrich Rothbauer, Oliver Poetz, Tina Romer, Andrea Buchfellner, Larisa Yurlova, Kourosh Zolghadr, Jaqueline Bogner, Benjamin Ruf, Christian Linke-Winnebeck, Michael Metterlein
Abstract: Provided herein is a novel epitope that can be used as a tag in methods for rapid and effective characterization, purification, and subcellular localization of polypeptides of interest, which comprise the tag. The tag is specifically recognized by an epitope specific antibody, which can be used to detect, capture, quantify, and/or purify polypeptides of interest that are tagged with the epitope. Also provided is novel epitope specific antibody.
Type:
Grant
Filed:
November 16, 2016
Date of Patent:
April 30, 2019
Assignees:
NMI NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DER UNIVERSITÄT TÜBINGEN, CHROMOTEK GMBH
Inventors:
Ulrich Rothbauer, Oliver Poetz, Tina Romer, Andrea Buchfellner, Larisa Yurlova, Kourosh Zolghadr, Jaqueline Bogner, Benjamin Ruf, Christian Linke-Winnebeck, Michael Metterlein
Abstract: Provided herein is a novel epitope that can be used as a tag in methods for rapid and effective characterization, purification, and subcellular localization of polypeptides of interest, which comprise the tag. The tag is specifically recognized by an epitope specific antibody, which can be used to detect, capture, quantify, and/or purify polypeptides of interest that are tagged with the epitope. Also provided is novel epitope specific antibody.
Type:
Grant
Filed:
January 15, 2016
Date of Patent:
November 13, 2018
Assignees:
ChromoTek GmbH, NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen
Inventors:
Ulrich Rothbauer, Oliver Poetz, Tina Romer, Andrea Buchfellner, Larisa Yurlova, Kourosh Zolghadr, Jaqueline Bogner, Benjamin Ruf