Abstract: A method of measuring an internal resistance of a battery cell and a device therefor are provided. A battery management device includes one or more passive balancing circuits provided for each of one or more battery cells, wherein each passive balancing circuit includes a balancing resistor and a switching element for selectively discharging each battery cell through the balancing resistor, and a control unit configured to determine an alternating current internal resistance of a target battery cell that is subject to cell balancing based on a voltage of the target battery cell before and after a target switching element that is the switching element corresponding to the target battery cell is turned on, and determine a direct current internal resistance of the target battery cell based on an amount of change in the voltage of the target battery cell during a time period after a predetermined time elapses from a time point when the target switching element is turned on.

Abstract: Provided is an artificial light source setting method and an artificial light source setting system for controlling secondary metabolites of plant and provide an artificial light source setting method and an artificial light source setting system for controlling secondary metabolites of plant, which predict content of the secondary metabolites of plant by measuring a light interception amount by using a cultivation environment of plant, a three-dimensional structure model of plant, and optical simulation and set an artificial light source according thereto.

Abstract: Disclosed is a composition for preventing or treating chronic obstructive pulmonary disease containing regorafenib as an active ingredient, and particularly a pharmaceutical composition for preventing or treating chronic obstructive pulmonary disease containing regorafenib or a pharmaceutically acceptable salt thereof as an active ingredient, in which regorafenib is capable of effectively inhibiting increased immune response, which is a symptom of chronic obstructive pulmonary disease, and of improving and restoring changed lung structure and damaged lung function, and can be effectively used for the manufacture of a medicament for the prevention, amelioration, or treatment of chronic obstructive pulmonary disease, such as emphysema, chronic bronchitis, asthma, or pneumonia.

Abstract: Provided is a microchip including a chip body having a first surface and a second surface facing the first surface, and an electrode layer on the second surface, wherein a surface roughness of the first surface is smaller than a surface roughness of an upper surface of the electrode layer such that van der Waals force between the first surface and an external contact surface are greater than van der Waals force between the electrode layer and the external contact surface.

Abstract: The present invention relates to: a novel 4-methoxy-2-phenethyl isoindolin-1-one derivative compound having the ability to promote the increase of nerve growth factor, the ability to promote the growth of nerve cells, and antineuritic activity; and a composition for preventing, improving and treating neurological diseases, comprising the same.

Abstract: The present invention relates to: a novel 6-methoxy-2-phenethyl isoindolin-1-one derivative compound having the ability to promote the increase of nerve growth factor, the ability to promote the growth of nerve cells, and antineuritic activity; and a composition for preventing, improving and treating neurological diseases, comprising the same.

Abstract: The present invention relates to a GRP78-derived peptide for screening highly efficient stem cells and the use thereof, and more particularly, to screening highly efficient stem cells using, as a marker, a GRP78-derived peptide capable of binding to the binding domain of GRP78 protein on the cell surface. According to the present invention, the GRP78-derived peptide comprising only a specific amino acid sequence capable of recognizing highly efficient stem cells, among the amino acid sequence of GRP78, makes it possible to screen only non-senescent young stem cells. In addition, when stem cells are treated with the GRP78-derived peptide or the GRP78-derived peptide is introduced into stem cells, the efficiency of the stem cells can be increased. Thus, the GRP78-derived peptide is useful for the production of stem cell therapy products having excellent efficacy.

Abstract: An insulation monitoring device, according to various embodiment of the present application, comprising an impedance formed between a power line and a ground of a system comprises, a signal generation circuit for applying a triangular wave signal to the power line through a signal measurement circuit, the signal measurement circuit for measuring a voltage difference across the detection resistor of the signal measurement circuit or a current flowing through the detection resistor when the triangular wave signal is applied to the impedance, a control circuit for obtaining an impedance value of the impedance based on at least one of the voltage difference and the current, and monitoring the impedance value.

Abstract: An atomic force microscope includes a sample stage on which a sample is placed, a cantilever including a probe tip, a laser radiating a laser beam to the cantilever, a photodetector receiving a laser beam reflected from the cantilever, a first camera photographing the sample and the cantilever, a second camera photographing the cantilever and the spot of the laser beam, and a processor electrically connected to the first and second cameras and the photodetector to process data acquired by the first and second cameras and the photodetector. An operation method of the atomic force microscope includes detecting the positions of the cantilever and the sample using the first camera, adjusting the position of the sample, detecting the positions of the laser and the cantilever using the second camera, aligning the laser, detecting the position of the laser beam using the photodetector, and aligning the position of the photodetector.

Abstract: Provided is a chimeric antigen receptor (CAR) specifically binding to CD138, an immune cell expressing same, and a pharmaceutical composition for the treatment or prevention of cancer including same as an active ingredient. It was confirmed that the CD138 chimeric antigen receptor (CAR)-expressing immune cell of the presently claimed subject matter efficiently exhibits strong cytotoxic ability against CD138-expressing (positive) cancer cells. Accordingly, it is expected that the CD138 chimeric antigen receptor (CAR)-expressing immune cell of the presently claimed subject matter can be utilized for the treatment of CD138-expressing (benign) cancer diseases.

Abstract: Provided are a composition for regulating stem cell function comprising the genus Lactobacillus bacteria-derived extracellular vesicles as an active ingredient, and a method for regulating a stem cell function using the same, wherein the genus Lactobacillus bacterial-derived extracellular vesicles have the effect of greatly improving the proliferation of stem cells, and the extracellular vesicles are naturally secreted from a symbiotic the genus Lactobacillus strain in human tonsillar tissue and are human-friendly and natural substances, and thus can be used in various research fields by promoting the proliferation of aged stem cells with minimal toxicity and side effects.

Abstract: Disclosed are a novel recombinant transition vector for increasing expression of a foreign protein in a native form without fusion partners, and a method for mass production of a foreign target protein using the same. The recombinant transition vector according to the present disclosure may allow a large amount of a foreign target protein with a high therapeutic and prophylactic value to be expressed in an insect cell. In particular, the vector may increase the expression of the foreign target protein in an own form thereof, not fused with other fusion partners. Therefore, the use of the recombinant transition vector may produce useful proteins such as antigens in insect cells at low cost and high efficiency.

Abstract: The present disclosure in some embodiments provides a coil alignment control method and a coil alignment control apparatus for the wireless charging of a mobile object, which perform a parallel alignment for aligning a power reception-side surface of a power reception coil of the mobile object to be parallel to a power transmission-side surface of a power transmission coil on a wireless-charging power transmission coil panel, perform a center alignment for the power reception coil and the power transmission coil to have central winding areas that are in alignment, and perform a proximity alignment for aligning the power reception coil to be in proximity to the power transmission coil by a preset proximity distance, thereby maximizing the wireless power transfer efficiency.

Abstract: A method of manufacturing a full-color holographic optical element in a full-color holographic optical element manufacturing apparatus including a lens and a holographic recording medium located farther away than a focal length of the lens, the method including: allowing a signal beam including a mixture of laser beams having wavelengths of R (Red), G (Green), and B (Blue) to be incident on the lens; and recording a hologram in such a manner that a reference beam including a mixture of laser beams having wavelengths of R, G, and B is allowed to be incident on the holographic recording medium, wherein the holographic recording medium is configured with a single medium.

Abstract: According to at least one embodiment, the present disclosure provides an apparatus for single-stage three-dimensional (3D) multi-object detection by using a LiDAR sensor to detect 3D multiple objects, comprising: a data input module configured to receive raw point cloud data from the LiDAR sensor; a BEV image generating module configured to generate bird's eye view (BEV) images from the raw point cloud data; a learning module configured to perform a deep learning algorithm-based learning task to extract a fine-grained feature image from the BEV images; and a localization module configured to perform a regression operation and a localization operation to find 3D candidate boxes and classes corresponding to the 3D candidate boxes for detecting 3D objects from the fine-grained feature image.

Abstract: Provided are a chimeric cytokine receptor capable of converting immunosuppressive signals to immunostimulatory signals, immune cells expressing same, and a method for treatment of cancer using the same, wherein the immune cells expressing the chimeric cytokine receptor convert immunosuppressive signals to immunostimulatory signals in a tumor microenvironment where immunosuppressive cytokines exist, thereby effectuating more potent cytotoxicity against cancer, and therefore the immune cells expressing the chimeric cytokine receptor are useful as a cell therapy product for treatment of cancer.

Abstract: A light source for plant cultivation includes a first light source emitting a first type of light for photosynthesis of a plant and a second light source emitting a second type of light for adjustment of phytochemicals in the plant. The first type of light has at least one peak in the visible spectrum, and the second type of light has a peak in a different wavelength band from the first light source. The second type of light has a peak in the wavelength band of about 360 nm to about 420 nm.

Abstract: Provided is a method and system for detecting a graph-based event in a social network, the method including generating a keyword graph based on social data collected from a social network system; separating the keyword graph into a plurality of candidate graphs through clustering; calculating a user interest for each of the plurality of candidate graphs based on a per-time variation of a social action associated with the social data; and determining k candidate graphs from among the plurality of candidate graphs as an event graph based on the user interest. Here, k denotes a natural number.

Abstract: The present invention provides a biomarker for predicting effectiveness for autoimmune disease treatment, a diagnostic kit, and a use for treatment. More particularly, the present invention provides a biomarker for predicting the effectiveness of mesenchymal stem cells (MSC) comprising the chemokine receptor CXCR3 for autoimmune disease treatment; a biomarker comprising the chemokine CXCL10 for predicting the prognosis of autoimmune disease treatment; a diagnostic kit comprising an agent capable of measuring the expression of the biomarker; and a pharmaceutical composition for prevention or treatment of an autoimmune disease, which comprises mesenchymal stem cells having an upregulated expression level of the chemokine receptor CXCR3.

Abstract: Disclosed herein is a pharmaceutical composition for treating or preventing inflammatory diseases or arthritis, which includes 2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition exhibits superior therapeutic efficacy against arthritis without any side effects such as toxicity, etc.