Patents Assigned to Ciba-Geigy Canada Ltd.
  • Vaccines with chimeric protein comprising gamma-interferon and leukotoxin derived from pasteurella haemolytica
    Patent number: 6096320
    Abstract: New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of an RTX cytotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: August 1, 2000
    Assignees: University of Saskatchewan, Ciba-Geigy Canada Ltd.
    Inventors: Andrew Potter, Manuel Campos, Huw P. A. Hughes
  • Chimeric protein comprising an RTX-family cytotoxin and interferon-2 or interferon
    Patent number: 5594107
    Abstract: New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of an RTX cytotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.
    Type: Grant
    Filed: December 20, 1993
    Date of Patent: January 14, 1997
    Assignees: University of Saskatchewan, Ciba-Geigy Canada Ltd.
    Inventors: Andrew Potter, Manuel Campos, Huw P. A. Hughes
  • Gamma-iterferon-leukotoxin gene fusions and uses thereof
    Patent number: 5273889
    Abstract: New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of leukotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.
    Type: Grant
    Filed: October 16, 1991
    Date of Patent: December 28, 1993
    Assignees: University of Saskatchewan, Ciba-Geigy Canada, Ltd.
    Inventors: Andrew Potter, Manuel Campos, Huw P. A. Hughes
  • Interleukin-2-leukotoxin gene fusions and uses thereof
    Patent number: 5238823
    Abstract: New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of leukotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.
    Type: Grant
    Filed: August 22, 1990
    Date of Patent: August 24, 1993
    Assignees: Veterinary Infectious Disease Organization, Ciba-Geigy Canada Ltd
    Inventors: Andrew Potter, Manuel Campos, Huw P. A. Hughes
  • Method for the prevention and treatment of bovine mastitis
    Patent number: 5124145
    Abstract: A method for treating or preventing mastitis in cows is disclosed. The method contemplates the intramammary injection of bovine interferon-gamma. Interferon-gamma can be administered prior to infection to effectively suppress the rate, severity, and duration of subsequent bacterial infection, or can be administered subsequent to infection to effectively treat mastitis.
    Type: Grant
    Filed: October 24, 1989
    Date of Patent: June 23, 1992
    Assignee: Ciba-Geigy Canada Ltd.
    Inventors: Lorraine M. Sordillo, Lorne A. Babiuk
  • Prevention and treatment of porcine haemophilus pneumonia (PHP)
    Patent number: 5049378
    Abstract: Methods of treating diseases in swine are disclosed using porcine interferon alpha and/or gamma.
    Type: Grant
    Filed: April 24, 1989
    Date of Patent: September 17, 1991
    Assignee: Ciba-Geigy Canada Ltd.
    Inventor: Manuel Campos