Patents Assigned to Cilltech R & D Limited
  • Modified antibody fragments
    Publication number: 20070059301
    Abstract: The present invention provides an antibody Fab or Fab? fragment to which at least one effector molecule is attached characterized in that the heavy chain in the fragment is not covalently bonded to the light chain and both the interchain cysteine of CL and the interchain cysteine of CH1 have been replaced with another amino acid.
    Type: Application
    Filed: July 1, 2004
    Publication date: March 15, 2007
    Applicant: Cilltech R & D Limited
    Inventors: David Humphreys, Sam Heywood, Bruce Carrington