Abstract: A drilling fixture for drilling either cylindrical or flat workpieces on or off center is disclosed. The fixture includes a base having a V-shaped groove for receiving larger cylindrical workpieces, a pair of smaller V-shaped openings in the side walls of the base for receiving smaller cylindrical workpieces, a cover attached to the base, and a rotatable, indexable drill bushing mounted to the cover. The larger and smaller V-shaped grooves intersect at a common workpiece center-line drilling point. Thumbscrews are provided to clamp the workpieces in the grooves. The drill bushing includes a series of different size drill guide holes spaced about the circumference of the bushing on a common radius for receiving predetermined drill bit diameters to guide the drill bits along their longitudinal axes during a drilling operation.