Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: A method and system for processing imaging data of a tissue in an individual following a change in oxygenation or blood flow in tissue, for assessing tissue function. Test images are registered with a baseline image, providing registered images. The registered images may be compared to assess variations in the change in the tissue in response to changes in oxygenation or blood flow of the tissue shown in the images. The change in oxygenation or blood flow in the tissue may be quantified and plotted in a parametric plot or displayed in a parametric map to assess whether the change in oxygenation or blood flow, corresponding to a change in signal intensity, is abnormal following a stress event or under other conditions, to assess microvascular or macrovascular function.

Abstract: The present disclosure relates to a method of assessing heart function and a system for assessing heart function. In detail, the present disclosure relates to a measuring a change in oxygenation or blood flow in the heart of the subject in response to a breathing maneuver and comparing the change in oxygenation or blood flow to a control. The change in oxygenation may be measured by segmenting an image of a heart, determining the signal intensity of a region of interest in a segment of the image and comparing the signal intensity to a control. An abnormal change in oxygenation blood flow or signal intensity in the heart compared to the control is indicative of reduced heart function. The disclosure further relates to a system for diagnosing heart disease which comprises an imaging device and processor configured to assess heart function.

Abstract: A method to determine myocardial wall dynamics and tissue characteristics using a method provided to determine myocardial wall dynamics and tissue characteristics using a 3D model of the myocardium. The method comprises generating an epicardial surface and an endocardial surface from a plurality of SAX and LAX slices; identifying a plurality of nodes on the epicardial and endocardial surfaces or in between these surfaces within the myocardium in a reference frame; defining a set of coefficients, each coefficient being associated with the respective location of the corresponding node in a phase; determining the coefficients and in this way determining the model; determining the myocardial wall dynamics in terms of strain values and displacements.