Abstract: A tubular shaped elongated catheter device assembly with a distal and a proximal end, comprising an intraluminal distal segment and an extraluminal proximal segment, comprising one or more chemical and/or biological agents, for interaction with bodily fluids of luminal organs, wherein the intraluminal segment comprises at least one expandable cross-sectional area which in its expanded state is smaller than the cross-sectional area of the luminal target site and wherein at least the expandable portion of the intraluminal segment is capable of interacting with at least one component of the bodily fluid via an interactive contact surface.

Abstract: The present invention relates to a catheter device comprising at least one pharmaceutically active compound, wherein the device is capable of releasing said pharmaceutically active compound such as angiogenesis promoting factors, inhibitors of an angiogenesis inhibiting factor or antibiotics over an extended period. It is preferred that the device is tubular and longitudinally extending device assembly with an intraluminal and an extraluminal segment and a proximal and a distal end, wherein the intraluminal segment comprises at least one reversibly expandable portion. Also envisaged is a catheter device for use in preventing a slow-healing or non-healing wound, diabetic foot or intoxication with bacterial toxins, or for treating or preventing bacterial or virus infections and/or medical complications during transplantation.

Abstract: The present invention relates to a filter device assembly implant comprising one or more chemical and/or biological agents wherein the implant is capable of recruiting a circulating tumor or circulating metastatic cell or motile parts of tumor cells and hereby removes said cell or motile part thereof from circulation. For this purpose the implant comprises an agent, which is capable of binding to a tumor marker. The present invention further relates to the use of the implant for the treatment of cancer or metastasis, or for preventing cancer or metastasis, as well as corresponding methods of treatment. Also envisaged is a method of manufacturing the filter device assembly implant.