Abstract: A brachytherapy device includes a bioabsorbable support and a plurality of microcapsules on the support. Each of the plurality of the microcapsules includes a plurality of microspheres and a bioabsorbable microcapsule wall that encloses the plurality of microspheres. The plurality of microspheres includes radiation-emitting microspheres comprising a radioactive material, radio-opaque microspheres comprising a radio-opaque material or a combination thereof.
Abstract: Methods of forming a low-dose-rate (LDR) brachytherapy device include depositing a solution comprising a soluble form of a radioactive material on a substrate. A water-insoluble form of the radioactive material is formed on the substrate by chemical precipitation and/or thermal decomposition.
Type:
Grant
Filed:
December 3, 2012
Date of Patent:
November 10, 2015
Assignee:
Civatech Oncology
Inventors:
Robert D. Black, David Wagner, Claudia Black
Abstract: Methods of forming a low-dose-rate (LDR) brachytherapy device include depositing a solution comprising a soluble form of a radioactive material on a substrate. A water-insoluble form of the radioactive material is formed on the substrate by chemical precipitation and/or thermal decomposition.
Abstract: Methods of forming a low-dose-rate (LDR) brachytherapy device include depositing a solution comprising a soluble form of a radioactive material on a substrate. A water-insoluble form of the radioactive material is formed on the substrate by chemical precipitation and/or thermal decomposition.
Type:
Grant
Filed:
May 1, 2009
Date of Patent:
December 4, 2012
Assignee:
Civatech Oncology
Inventors:
Robert D. Black, David Wagner, Claudia Black
Abstract: A low-dose-rate (LDR) brachytherapy device having a spatiotemporal radiation profile includes an elongated body having a radioactive material in a spatial pattern to provide a spatial radiation profile with a radiation intensity that varies along a length of the elongated body. The radioactive material includes at least first and second radioisotopes having at least first and second respective decay profiles that together provide a temporal radiation profile that is different from the first and second decay profiles. The spatial radiation profile and the temporal radiation profile form a net spatiotemporal radiation profile configured to provide a radiotherapy plan for a patient.