Patents Assigned to CLANOTECH AB
  • Quinoline compounds which are anti-angiogenic integrin alpha5 beta1 inhibitors for use in the treatment of fibrosis or fibrosis-related diseases
    Patent number: 9376393
    Abstract: A new medical therapy, and more particularly certain quinoline compounds which are anti-angiogenic integrin aplha5beta1 inhibitors, for use in the treatment of fibrosis, or a fibrosis-related disease, such as a fibrotic disease affecting the lung, liver, kidney, skin, epidermis, endodermis, muscle, tendon, cartilage, heart, stomach, large intestine, small intestine, colon, uterus, nervous system, testis, adrenal gland, artery, vein, biliary tract, or eye.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: June 28, 2016
    Assignee: Clanotech AB
    Inventor: Yihai Cao
  • Quinoline derivatives and their use as tyrosine kinase inhibitors
    Patent number: 8957092
    Abstract: A compound of formula 6-(methylcarbamoyl)-4-[(4-methylphenyl)amino]quinoline-3-carboxylic acid, and pharmaceutically acceptable salts thereof, is provided. The compound can be used to treat cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke, ischemic myocardium, atherosclerosis, macular edema and psoriasis.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: February 17, 2015
    Assignee: ClanoTech AB
    Inventors: Jacob Westman, Natalia Nekhotiaeva, Johan Wannberg, Ulrika Backman, Johan Malm
  • Quinoline derivatives and their use as tyrosine kinase inhibitors
    Patent number: 8557843
    Abstract: A compound of formula (I) as well as pharmaceutically acceptable salts thereof. A pharmaceutical composition having a therapeutically effective amount of the compound. The compound is useful for the treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke, ischemic myocardium, atherosclerosis, macular edema or psoriasis.
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: October 15, 2013
    Assignee: ClanoTech AB
    Inventors: Jacob Westman, Natalia Nekhotiaeva, Johan Wannberg, Ulrika Backman, Johan Malm
  • SUBSTITUTED QUINOLINES FOR USE AS VEGF INHIBITORS
    Publication number: 20120065199
    Abstract: A compound of formula (I) as well as pharmaceutically acceptable salts thereof and pharmaceutical compositions including a therapeutically effective amount of the compounds. The compound is useful in treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke, ischemic myocardium, atherosclerosis, macular edema and psoriasis.
    Type: Application
    Filed: May 20, 2010
    Publication date: March 15, 2012
    Applicant: CLANOTECH AB
    Inventors: Johan Malm, Rune Ringom, Patrizia Caldirola, Jacob Westman
  • QUINOLINE DERIVATIVES AND THEIR USE AS TYROSINE KINASE INHIBITORS
    Publication number: 20110053976
    Abstract: A compound of formula (I) as well as pharmaceutically acceptable salts thereof. A pharmaceutical composition having a therapeutically effective amount of the compound. The compound is useful for the treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke, ischemic myocardium, atherosclerosis, macular edema or psoriasis.
    Type: Application
    Filed: November 14, 2008
    Publication date: March 3, 2011
    Applicant: CLANOTECH AB
    Inventors: Jacob Westman, Natalia Nekhotiaeva, Johan Wannberg, Ulrika Backman, Johan Malm