Abstract: Method for treatment of inflammatory and fibrotic conditions in vivo using pure rhUG is disclosed. Method for treating or preventing inflammatory or fibrotic conditions characterized by a deficiency of endogenous functional UG is also disclosed. Compositions containing pure rhUG, optionally also containing lung surfactant, and assay procedures for detection of UG-fibronectin complexes, are also provided.
Type:
Grant
Filed:
May 28, 1997
Date of Patent:
July 3, 2001
Assignee:
Claragen, Inc. and U.S. Government
Inventors:
Aprile L. Pilon, Anil B. Mukherjee, Zhongjian Zhang