Abstract: A process is disclosed for manufacturing N-methyl-N-phenylaminoacrolein of formula (I) which comprises reacting N-methylformanilide and an alkyl vinyl ether of formula (III) wherein R is a C3–C4 alkyl, said process being characterized in that the reaction between N-methylformanilide and said alkyl vinyl ether of formula (III) is carried out in the presence of phosgene, diphosgene or triphosgene in a solvent selected from dioxane, acetonitrile and/or chlorobenzene.
Type:
Grant
Filed:
May 7, 2004
Date of Patent:
August 15, 2006
Assignee:
Clariant Life Science Molecules (Italia) S.p.A.
Abstract: A new method is described here for the synthesis of (S)-N-tert-butyl-1,2,3,4-tetrahydroiso-quinoline-3-carboxamide comprising the following steps: a) (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is reacted with formic acid to give the compound of formula: b) the compound thus obtained is reacted with tert-butylamine to give the compound of formula: c) the compound thus obtained is then treated with acids to give the desired compound. The method in question makes it possible to obtain (S)-N-tert-butyl-1,2,3,4-tetrahydroiso-quinoline-3-carboxamide with high yields and purity without using toxic and hazardous reagents.
Type:
Grant
Filed:
September 27, 2001
Date of Patent:
May 17, 2005
Assignee:
Clariant Life Science Molecules (Italia) S.p.A.
Abstract: A method for determining operational characteristics of capacitive sensors adapted for self-calibration includes the steps of providing at least one capacitive sensor having a suspended element and a pick-up plate. An AC input signal is applied to one of the plates, while force is provided between the plates, the force capable of variation. At least one operational characteristic of capacitive sensors can be determined, such as the suspended element spring constant and the gap distance between the plates. A capacitive sensor system adapted for self-calibration includes at least one capacitive sensor having a suspended element and a pick-up plate, a self-testing and calibration network, and a structure for generating force between the plates, the force capable of variation.
Type:
Application
Filed:
April 17, 2001
Publication date:
October 31, 2002
Applicant:
CLARIANT LIFE SCIENCE MOLECULES (Italia) S.p.A