Abstract: An orally or parenterally administrable composition which comprises the following components: (a) L-carnitine inner salt or a pharmacologically acceptable salt thereof; (b) acetyl L-carnitine inner salt or a pharmacologically acceptable salt thereof; (c) ?-lipoic acid; (d) coenzyme Q10; (e) Vitamin E; and (f) selenomethionine, suitable for counteracting oxidative stress and use thereof are disclosed.

Abstract: A pharmaceutical composition administerable either orally or parenterally, comprising a therapeutically effective amount of an acyl-carnitine, or a pharmaceutically acceptable salt, ester or amide thereof, wherein the acyl radical is selected from the group formed by acetyl, propionyl, butyryl, hydroxybutyryl and acetoacetyl is useful in the therapeutical treatment of patients with impaired cerebral metabolism, as for instance in the states of senile and presenile psychomotor involution and in senile and presenile dementia.

Abstract: A process for manufacturing the D camphorate of L carnitinamide and the D camphorate of D carnitinamide is disclosed, wherein D,L carnitinamide hydrochloride is converted to D,L carnitinamide free base which directly reacts with D camphoric acid either as an aqueous suspension or in solid form, thus obtaining a solution of D camphorate of D,L carnitinamide. The resolution of the optical isomers is achieved by drying this solution and taking up the residue with isopropanol, whereupon the D camphorate of L carnitinamdide crystallizes out of the isopropanol solution and the D camphorate of D carnitinamide remains in solution.