Patents Assigned to CLAVIS PHARMA AG
  • Publication number: 20090209477
    Abstract: The present invention is directed toward compounds of Formula (I) as follows: wherein, R is H, R5C(O), R5CH2OC(O), or R5CH2NHC(O); R1 is where the crossing dashed line illustrates the bond formed joining R1 to the molecule of Formula (I); R2 and R3 are independently OH or H, provided that R2 and R3 are not simultaneously OH; R4 is H, R5C(O), R5CH2OC(O), or R5CH2NHC(O), provided that R and R4 are not simultaneously H; and R5 has the general formula: CH3—(CH2)n—(CH?CH—CH2)m—CH?CH—(CH2)k—; k is an integer from 0 to 7; m is an integer from 0 to 2; and n is an integer from 0 to 10, or a pharmaceutical salt thereof. Methods of making and using these compounds are also disclosed.
    Type: Application
    Filed: September 25, 2008
    Publication date: August 20, 2009
    Applicants: MOUNT SINAI SCHOOL OF MEDICINE, CLAVIS PHARMA AG
    Inventors: Lewis Silverman, James Holland, Marit Liland Sandvold, Finn Myhren, Ole Henrik Eriksen