Patents Assigned to CLEA TECHNOLOGIES BV
  • Method for preparing hybrid cross-linked enzyme-silica aggregates
    Patent number: 8835143
    Abstract: The invention relates to a method for the preparation of hybrid cross-linked enzyme-silica aggregates including the steps of taking up enzyme molecules in a solvent, precipitating the enzyme molecules using a precipitation agent, and adding an alkoxysilane and crosslinking the mixture of alkoxysilane and precipitated enzyme aggregates, using a crosslinking agent comprising an aldehyde, to obtain hybrid crosslinked enzyme-silica aggregates.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: September 16, 2014
    Assignee: Clea Technologies BV
    Inventors: Willem Robert Klaas Schoevaart, Lukas Michael Van Langen, Ronald Tako Marinus van Den Dool, Johannes Wilhelmus Leonardus Boumans
  • Method for the Preparation of Cross-Linked Enzyme Aggregates with Improved Properties
    Publication number: 20080296231
    Abstract: The invention relates to a method for the preparation of cross-linked enzyme aggregates, which method is characterised by the following steps: i. generating aldehyde groups on enzyme molecules that may or may not be dissolved in a suitable solvent; ii. precipitating the enzyme molecules using a suitable precipitation agent; iii. cross-linking the precipitated enzyme molecules provided with aldehyde groups, using an amine composition, yielding cross-linked enzyme aggregates with improved properties.
    Type: Application
    Filed: October 27, 2005
    Publication date: December 4, 2008
    Applicant: CLEA TECHNOLOGIES BV
    Inventors: Willem Robert Klaas Schoevaart, Lukas Michael Van Langen, Ronald Tako Marinus Van Den Dool, Johannes Wilhelmus Leonardus Boumans