Abstract: A system for mixing and delivering content is disclosed. The system includes an applicator, a needle assembly, and a micro seal. The applicator includes two component chambers separate from one another, each component chamber including at least one output port on a distal end thereof and an applicator hub disposed on a distal end of the applicator adjacent to the at least one output port of each component chamber. The needle assembly includes an elongate hollow stylet having a plurality of lumens therein and a needle hub having an interior cannula fluidly coupled to the elongate hollow stylet. The micro seal is disposed within the applicator hub. The micro seal is configured to receive the interior cannula of the needle hub to establish a fluid coupling between each of the two component chambers with a respective one of the lumens within the elongate hollow stylet.

Abstract: A medical device (10) for dilating an endovascular lumen and having a collapsed configuration and an expanded configuration, the medical device comprising a stem (20) extending along a longitudinal axis of the device; a first plate (30) disposed partly around the stem (20); a second plate (40) disposed partly around the stem (20) angularly separated in a circumferential direction from the first plate (30); and an expansion mechanism (50) configured to move each of the first plate (30) and/or the second plate (40) radially outwardly when the medical device (10) is expanded from the collapsed configuration to the expanded configuration.

Abstract: A component delivery system is disclosed. The component delivery system includes an applicator including two chambers separate from one another, each chamber including at least one output port on a distal end thereof for receiving corresponding pistons. The component delivery system further includes a two-piece alignment fixture removably couplable to the applicator and a two-piece piston insert removably couplable to the pistons, the two-piece piston insert engagable with the two-piece alignment fixture to prevent removal of the pistons from the two chambers.

Abstract: For treating a treatment area in the vasculature, this disclosure relates to a first, pre-dilation catheter having a first shaft including a first distal portion adapted for positioning at the treatment area and a first proximal portion including a first marking at a first location. A second, dilation catheter includes a second shaft including a second distal portion adapted for positioning at the treatment area and a second proximal portion including a second marking at a second location substantially matching a first location of the first marking. Related methods are disclosed.

Abstract: A control handle for an atherectomy device comprising a housing and a drive module for rotating an abrasive head of the atherectomy device. The drive module is moveable relative to the housing in a longitudinal stroke motion. The control handle further comprises a rotary indexing mechanism connected to the drive module. The rotary indexing mechanism is configured to rotate the drive module by a pre-determined amount after a longitudinal stroke.

Abstract: A balloon catheter includes an elongated, tubular shaft having a proximal end and a distal end, and a balloon positioned along the distal end of the shaft. A portion of a wall of the balloon partially comprises a coextruded radiopaque material. Related aspects and methods are also disclosed.

Abstract: A parison for being blow molded into a medical balloon for a catheter includes a first tubular layer having a functional modification and a second tubular layer adapted for bonding with the first tubular layer to form the blow molded balloon. Related methods are also disclosed.

Abstract: A balloon catheter for use with a guidewire includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is connected to the distal end of the shaft, the balloon including a working surface. A radiopaque identifier is provided for identifying the working surface. A receiver adjacent the proximal end of the shaft is adapted for allowing the shaft to move relative to the receiver in at least the longitudinal direction.

Abstract: An apparatus is for use in connection with an implement for being inserted into a vascular space. The apparatus includes a body having a passage adapted for receiving the implement. A counter is provided for counting the amount the implement moves through the passage of the body. A kit may include a first counter adapted for use with a first device having a first diameter for being inserted into the vasculature, and a second counter adapted for use with a second device having a second diameter for being inserted into the vasculature. Related methods are also described.

Abstract: An embolisation device (300, 500) for promoting clot formation in a body lumen comprising two or more linearly connected sections (305, 505), each section comprising one or more bristle segments (310, 510) comprising a core and a plurality of flexible bristles (330, 530) extending at least radially outwardly from the core, the flexible bristles having a collapsed delivery configuration and an expanded deployed configuration in which the bristles extend at least radially outwardly from the core to anchor the bristle segment in a bodily lumen, wherein: each pair of adjacent sections are connected via a respective connecting mechanism; and when the bristle segments are in the expanded deployed configuration, each respective connecting mechanism is selectively changeable from a first configuration attaching the pair of adjacent sections, to a second configuration detaching the pair of adjacent sections.

Abstract: A connector for transfer of an implantable device from a loading tube to a delivery catheter, comprising: a first connecting portion (110) having a first distal end (120) configured to receive a delivery catheter (190); a second connecting portion (130) having a second proximal end (150) configured to receive a loading tube (180) extending towards the first distal end, the second connecting portion movably connected to the first connecting portion; and a biasing element (160) connecting the first and second connecting portions, having a relaxed configuration in which the first distal end and the second proximal end are spaced apart by a predetermined distance, and configured to bias the first distal end and second proximal end to the relaxed configuration when the first distal end and second proximal end are moved apart; such that when the loading tube is received, upon receiving the delivery catheter by the first connecting portion, the loading tube is biased to the delivery catheter to form a connection for

Abstract: An apparatus includes a catheter having a balloon including at least one first radiopaque marking. A guidewire guides the balloon to the treatment area, and includes at least one second radiopaque marking adapted for corresponding to the at least one first radiopaque marking of the balloon when positioned at the treatment area. Related aspects and methods are disclosed.

Abstract: A balloon (12) having a drug carried on a working surface (W) of the balloon wall and a radiopaque identifier (30) identifying the location of the drug (D) on the balloon (12), wherein a portion of the balloon is coated with a radiopaque material to which a drug formulation adheres, and uncoated areas are not covered by the drug (D) or the drug (D) is adhered to the working surface (W), that is not treated with radiopaque material.

Abstract: An apparatus is for use in connection with an implement for being inserted into a vascular space. The apparatus includes a body having a passage adapted for receiving the implement. A counter is provided for counting the amount the implement moves through the passage of the body. A kit may include a first counter adapted for use with a first device having a first diameter for being inserted into the vasculature, and a second counter adapted for use with a second device having a second diameter for being inserted into the vasculature. Related methods are also described.

Abstract: A parison for being blow molded into a medical balloon for a catheter includes a first tubular layer having a functional modification and a second tubular layer adapted for bonding with the first tubular layer to form the blow molded balloon. Related methods are disclosed.

Abstract: A balloon catheter (10) with a shaft (14,24) extending in a longitudinal direction and having a proximal end and a distal end and an inflatable balloon positioned along the shaft. The balloon (12) includes at least one portion connected to the shaft and adapted for moving toward the proximal end thereof when the balloon is inflated. Related aspects are disclosed.

Abstract: There is provided a laminate membrane for an implant, comprising: an inner layer having an inner layer thickness; a first covering layer disposed on one side of the inner layer, the first covering layer having a first covering layer thickness; and a second covering layer disposed on another side of the inner layer, the second covering layer having a second covering layer thickness.

Abstract: There is provided an implant system comprising: a delivery wire assembly having a female detachment mechanism component; and an implant having a male detachment mechanism component, wherein the female detachment mechanism component comprises a coil configured to receive the male detachment mechanism component such that the male detachment mechanism component is attachable to the female detachment mechanism component.

Abstract: A balloon catheter adapted for use with a guidewire includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including first and second spaced ends and a working surface between the ends. An insert located within the interior compartment of the balloon includes at least a radiopaque portion separate from the shaft. Related methods are also disclosed.

Abstract: An embolisation device (10) for promoting clot formation in a bodily lumen (L) and having a collapsed delivery configuration for delivery of the embolisation device (10) into, and retrieval of the embolisation device (10) from, the bodily lumen (L) and an expanded deployed configuration for anchoring the embolisation device (10) in the bodily lumen (L). The embolisation device (10) comprises a tubular cage (20) having a collapsed delivery configuration and an expanded deployed configuration. The embolisation device further comprises an embolisation member (30) disposed in the tubular cage (20), the embolisation member (30) comprising a stem (31) and a plurality of flexible bristles (32) extending outwardly from the stem, the plurality of flexible bristles having a collapsed delivery configuration and an expanded deployed configuration.