Abstract: A system for mixing and delivering content is disclosed. The system includes an applicator, a needle assembly, and a micro seal. The applicator includes two component chambers separate from one another, each component chamber including at least one output port on a distal end thereof and an applicator hub disposed on a distal end of the applicator adjacent to the at least one output port of each component chamber. The needle assembly includes an elongate hollow stylet having a plurality of lumens therein and a needle hub having an interior cannula fluidly coupled to the elongate hollow stylet. The micro seal is disposed within the applicator hub. The micro seal is configured to receive the interior cannula of the needle hub to establish a fluid coupling between each of the two component chambers with a respective one of the lumens within the elongate hollow stylet.

Abstract: A medical device (10) for dilating an endovascular lumen and having a collapsed configuration and an expanded configuration, the medical device comprising a stem (20) extending along a longitudinal axis of the device; a first plate (30) disposed partly around the stem (20); a second plate (40) disposed partly around the stem (20) angularly separated in a circumferential direction from the first plate (30); and an expansion mechanism (50) configured to move each of the first plate (30) and/or the second plate (40) radially outwardly when the medical device (10) is expanded from the collapsed configuration to the expanded configuration.

Abstract: A component delivery system is disclosed. The component delivery system includes an applicator including two chambers separate from one another, each chamber including at least one output port on a distal end thereof for receiving corresponding pistons. The component delivery system further includes a two-piece alignment fixture removably couplable to the applicator and a two-piece piston insert removably couplable to the pistons, the two-piece piston insert engagable with the two-piece alignment fixture to prevent removal of the pistons from the two chambers.

Abstract: For treating a treatment area in the vasculature, this disclosure relates to a first, pre-dilation catheter having a first shaft including a first distal portion adapted for positioning at the treatment area and a first proximal portion including a first marking at a first location. A second, dilation catheter includes a second shaft including a second distal portion adapted for positioning at the treatment area and a second proximal portion including a second marking at a second location substantially matching a first location of the first marking. Related methods are disclosed.

Abstract: A control handle for an atherectomy device comprising a housing and a drive module for rotating an abrasive head of the atherectomy device. The drive module is moveable relative to the housing in a longitudinal stroke motion. The control handle further comprises a rotary indexing mechanism connected to the drive module. The rotary indexing mechanism is configured to rotate the drive module by a pre-determined amount after a longitudinal stroke.

Abstract: A balloon catheter includes an elongated, tubular shaft having a proximal end and a distal end, and a balloon positioned along the distal end of the shaft. A portion of a wall of the balloon partially comprises a coextruded radiopaque material. Related aspects and methods are also disclosed.

Abstract: A parison for being blow molded into a medical balloon for a catheter includes a first tubular layer having a functional modification and a second tubular layer adapted for bonding with the first tubular layer to form the blow molded balloon. Related methods are also disclosed.

Abstract: A balloon catheter for use with a guidewire includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is connected to the distal end of the shaft, the balloon including a working surface. A radiopaque identifier is provided for identifying the working surface. A receiver adjacent the proximal end of the shaft is adapted for allowing the shaft to move relative to the receiver in at least the longitudinal direction.

Abstract: An apparatus is for use in connection with an implement for being inserted into a vascular space. The apparatus includes a body having a passage adapted for receiving the implement. A counter is provided for counting the amount the implement moves through the passage of the body. A kit may include a first counter adapted for use with a first device having a first diameter for being inserted into the vasculature, and a second counter adapted for use with a second device having a second diameter for being inserted into the vasculature. Related methods are also described.

Abstract: An apparatus includes a catheter having a balloon including at least one first radiopaque marking. A guidewire guides the balloon to the treatment area, and includes at least one second radiopaque marking adapted for corresponding to the at least one first radiopaque marking of the balloon when positioned at the treatment area. Related aspects and methods are disclosed.

Abstract: A balloon (12) having a drug carried on a working surface (W) of the balloon wall and a radiopaque identifier (30) identifying the location of the drug (D) on the balloon (12), wherein a portion of the balloon is coated with a radiopaque material to which a drug formulation adheres, and uncoated areas are not covered by the drug (D) or the drug (D) is adhered to the working surface (W), that is not treated with radiopaque material.

Abstract: An apparatus is for use in connection with an implement for being inserted into a vascular space. The apparatus includes a body having a passage adapted for receiving the implement. A counter is provided for counting the amount the implement moves through the passage of the body. A kit may include a first counter adapted for use with a first device having a first diameter for being inserted into the vasculature, and a second counter adapted for use with a second device having a second diameter for being inserted into the vasculature. Related methods are also described.

Abstract: A parison for being blow molded into a medical balloon for a catheter includes a first tubular layer having a functional modification and a second tubular layer adapted for bonding with the first tubular layer to form the blow molded balloon. Related methods are disclosed.

Abstract: A balloon catheter (10) with a shaft (14,24) extending in a longitudinal direction and having a proximal end and a distal end and an inflatable balloon positioned along the shaft. The balloon (12) includes at least one portion connected to the shaft and adapted for moving toward the proximal end thereof when the balloon is inflated. Related aspects are disclosed.

Abstract: A balloon catheter adapted for use with a guidewire includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including first and second spaced ends and a working surface between the ends. An insert located within the interior compartment of the balloon includes at least a radiopaque portion separate from the shaft. Related methods are also disclosed.

Abstract: An embolisation device (10) for promoting clot formation in a bodily lumen (L) and having a collapsed delivery configuration for delivery of the embolisation device (10) into, and retrieval of the embolisation device (10) from, the bodily lumen (L) and an expanded deployed configuration for anchoring the embolisation device (10) in the bodily lumen (L). The embolisation device (10) comprises a tubular cage (20) having a collapsed delivery configuration and an expanded deployed configuration. The embolisation device further comprises an embolisation member (30) disposed in the tubular cage (20), the embolisation member (30) comprising a stem (31) and a plurality of flexible bristles (32) extending outwardly from the stem, the plurality of flexible bristles having a collapsed delivery configuration and an expanded deployed configuration.

Abstract: Treating a treatment area in the vasculature includes a first catheter adapted for positioning at the treatment area, said first catheter including a first balloon having a transient radiopaque material corresponding to the treatment area. A second catheter adapted for positioning at a treatment area includes a treatment that substantially matches the transient radiopaque material, preferably so that the length and/or position of the treatment corresponds to the length and/or position of the transient radiopaque material. Related kits, assemblies, and methods are also described.

Abstract: A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed.

Abstract: A catheter structure, such as a balloon catheter (30), guidewire, or the like, with markings (32) perceptible outside of the vasculature is for use in determining at a location external to the body the position of the catheter structure relative to a treatment area. Related kits are also disclosed.

Abstract: A parison for being blow molded into a medical balloon for a catheter includes a first tubular layer having a functional modification and a second tubular layer adapted for bonding with the first tubular layer to form the blow molded balloon. Related methods are also disclosed.