Patents Assigned to Clemson University of Research Foundation
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Patent number: 7713543Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.Type: GrantFiled: July 10, 2007Date of Patent: May 11, 2010Assignee: Clemson University Research FoundationInventors: Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu
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Patent number: 7691417Abstract: A compound derived from an extract of vegetative tissue of plants of the Genus Shortia demonstrates antitcarcinogenic potential by inhibiting the growth and development formation of tumors in living tissue in response to an organism known to cause the initiation of tumors in living tissue and by reducing mutation rates in living tissues exposed to a known mutagen.Type: GrantFiled: September 1, 2005Date of Patent: April 6, 2010Assignee: Clemson University Research FoundationInventors: Sandra L. Gray, N. Dwight Camper
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Patent number: 7651615Abstract: The present disclosure is generally directed to a process for decreasing waste material. The process includes loading organic material into a vessel, supplying ozone and water into the vessel, separating the organic material into solid material and liquid material, and reconditioning water from the liquid material for use again. The ozone oxidizes and breaks down at least a portion of the organic material.Type: GrantFiled: December 22, 2006Date of Patent: January 26, 2010Assignee: Clemson University Research FoundationInventor: Annel Kay Greene
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Publication number: 20090277831Abstract: A mixed culture of Dehalococcoides species is provided that has an ability to catalyze the complete dechlorination of polychlorinated ethenes such as PCE, TCE, cDCE, 1,1-DCE and vinyl chloride as well as halogenated ethanes such as 1,2-DCA and EDB. The mixed culture demonstrates the ability to achieve dechlorination even in the presence of high source concentrations of chlorinated ethenes.Type: ApplicationFiled: May 7, 2008Publication date: November 12, 2009Applicants: Washington Savannah River Co, LLC, Clemson University Research FoundationInventors: Christopher E. Bagwell, David L. Freedman, Robin Brigmon, William B. Bratt, Elizabeth A. Wood
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Patent number: 7598751Abstract: Embodiments according to the present invention provide an Impedance-based Arc-Fault Determination Device (IADD) and method that, when attached to an electrical node on the power system and through observations on voltage, current and phase shift with a step load change, determine the effective Thevenin equivalent circuit or Norton equivalent circuit at the point of test. The device and method determine the expected bolted fault current at the test location of interest, which enables calculation of incident energy and the assignment of a flash-hazard risk category.Type: GrantFiled: August 14, 2007Date of Patent: October 6, 2009Assignees: Clemson University Research Foundation, Duke Energy Carolinas, LLCInventors: Edward Randolph Collins, Jr., Timothy Lee Smith, Randall J. Emanuel
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Patent number: 7349731Abstract: The invention provides a means to produce reconstructed refractive index spatial maps that reveal and allow visual separation of normal soft tissue and certain types of tumors. Detector fiber optic bundles positioned on the surface of a soft tissue organ receive and transmit scattered light data, from light in the near-infrared portion of the spectrum delivered to the surface of the organ by separate fiber optic bundles to a computer. Based on an established grid and certain assumed values, the data are analyzed by means of a complex algorithm to produce calculated refractive index values. Through iteration, the values are recalculated to minimize the difference between the observed scattering and calculated values to yield a stable map indicating spatial variation in refractive index and such variation in the form of displayed images indicates the presence of tumors in normal soft tissue.Type: GrantFiled: May 29, 2003Date of Patent: March 25, 2008Assignee: Clemson University Research FoundationInventor: Huabei Jiang
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Patent number: 7252834Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.Type: GrantFiled: March 23, 2006Date of Patent: August 7, 2007Assignee: Clemson University Research Foundation (CURF)Inventors: Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu
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Patent number: 6761957Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: November 18, 1999Date of Patent: July 13, 2004Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6617025Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: October 20, 2000Date of Patent: September 9, 2003Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6610402Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: July 2, 2001Date of Patent: August 26, 2003Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6605349Abstract: A deformable, shrinkable fiber that is dimensionally stable at normal body temperatures of approximately 37° C. in the dry state, but is dimensionally unstable (i.e. shrinks and distorts) when wet at the same temperature. The fiber comprises a fiber forming polymer that has a dry glass transition temperature (“dry Tg”) of greater than or equal to 42° C. and a wet glass transition temperature (“wet Tg”) of less than or equal to 32° C. A method of making said fiber and absorbent article(s) made therefrom are also disclosed.Type: GrantFiled: August 19, 2002Date of Patent: August 12, 2003Assignee: Clemson University Research FoundationInventor: Bobby Mal Phillips
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Publication number: 20030114068Abstract: An article of manufacture particularly suitable as wallboard, the article comprising a bonded nonwoven structure sandwiched between two layers of paper, wherein the bonded nonwoven structure comprises a binder and a load-bearing fiber wherein the load-bearing fiber has a shape factor between about 2 and 6, a short range distortion factor (SRDF) between about 5 and 70, a long range distortion factor (LRDF) between about 0.1 and 0.6, and a denier per filament (dpf) between about 3 and 200. A method of making the article is also disclosed.Type: ApplicationFiled: December 13, 2002Publication date: June 19, 2003Applicant: Clemson University Research FoundationInventors: Bobby Mal Phillips, Leron Ronnie Dean
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Publication number: 20030044601Abstract: A deformable, shrinkable fiber that is dimensionally stable at normal body temperatures of approximately 37° C. in the dry state, but is dimensionally unstable (i.e. shrinks and distorts) when wet at the same temperature. The fiber comprises a fiber forming polymer that has a dry glass transition temperature (“dry Tg”) of greater than or equal to 42° C. and a wet glass transition temperature (“wet Tg”) of less than or equal to 32° C. A method of making said fiber and absorbent article(s) made therefrom are also disclosed.Type: ApplicationFiled: August 19, 2002Publication date: March 6, 2003Applicant: Clemson University Research FoundationInventor: Bobby Mal Phillips
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Patent number: 6509093Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: October 20, 2000Date of Patent: January 21, 2003Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6497955Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: October 20, 2000Date of Patent: December 24, 2002Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6495256Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: October 20, 2000Date of Patent: December 17, 2002Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6492023Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: October 20, 2000Date of Patent: December 10, 2002Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6468653Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: October 20, 2000Date of Patent: October 22, 2002Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6465096Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: October 20, 2000Date of Patent: October 15, 2002Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
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Patent number: 6451428Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.Type: GrantFiled: October 20, 2000Date of Patent: September 17, 2002Assignee: Clemson University Research FoundationInventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia