Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.
Type:
Grant
Filed:
March 23, 2006
Date of Patent:
August 7, 2007
Assignee:
Clemson University Research Foundation (CURF)
Inventors:
Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
November 18, 1999
Date of Patent:
July 13, 2004
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
September 9, 2003
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
July 2, 2001
Date of Patent:
August 26, 2003
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: A deformable, shrinkable fiber that is dimensionally stable at normal body temperatures of approximately 37° C. in the dry state, but is dimensionally unstable (i.e. shrinks and distorts) when wet at the same temperature. The fiber comprises a fiber forming polymer that has a dry glass transition temperature (“dry Tg”) of greater than or equal to 42° C. and a wet glass transition temperature (“wet Tg”) of less than or equal to 32° C. A method of making said fiber and absorbent article(s) made therefrom are also disclosed.
Abstract: An article of manufacture particularly suitable as wallboard, the article comprising a bonded nonwoven structure sandwiched between two layers of paper, wherein the bonded nonwoven structure comprises a binder and a load-bearing fiber wherein the load-bearing fiber has a shape factor between about 2 and 6, a short range distortion factor (SRDF) between about 5 and 70, a long range distortion factor (LRDF) between about 0.1 and 0.6, and a denier per filament (dpf) between about 3 and 200. A method of making the article is also disclosed.
Abstract: A deformable, shrinkable fiber that is dimensionally stable at normal body temperatures of approximately 37° C. in the dry state, but is dimensionally unstable (i.e. shrinks and distorts) when wet at the same temperature. The fiber comprises a fiber forming polymer that has a dry glass transition temperature (“dry Tg”) of greater than or equal to 42° C. and a wet glass transition temperature (“wet Tg”) of less than or equal to 32° C. A method of making said fiber and absorbent article(s) made therefrom are also disclosed.
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
January 21, 2003
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
December 24, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
December 17, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
December 10, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
October 22, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
October 15, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
September 17, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
August 20, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
July 30, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
June 11, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
November 15, 1999
Date of Patent:
May 14, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
November 22, 1999
Date of Patent:
March 5, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
Type:
Grant
Filed:
November 16, 1999
Date of Patent:
March 5, 2002
Assignee:
Clemson University Research Foundation
Inventors:
Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia