Patents Assigned to Clemson University of Research Foundation
  • Patent number: 7713543
    Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: May 11, 2010
    Assignee: Clemson University Research Foundation
    Inventors: Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu
  • Patent number: 7691417
    Abstract: A compound derived from an extract of vegetative tissue of plants of the Genus Shortia demonstrates antitcarcinogenic potential by inhibiting the growth and development formation of tumors in living tissue in response to an organism known to cause the initiation of tumors in living tissue and by reducing mutation rates in living tissues exposed to a known mutagen.
    Type: Grant
    Filed: September 1, 2005
    Date of Patent: April 6, 2010
    Assignee: Clemson University Research Foundation
    Inventors: Sandra L. Gray, N. Dwight Camper
  • Patent number: 7651615
    Abstract: The present disclosure is generally directed to a process for decreasing waste material. The process includes loading organic material into a vessel, supplying ozone and water into the vessel, separating the organic material into solid material and liquid material, and reconditioning water from the liquid material for use again. The ozone oxidizes and breaks down at least a portion of the organic material.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: January 26, 2010
    Assignee: Clemson University Research Foundation
    Inventor: Annel Kay Greene
  • Publication number: 20090277831
    Abstract: A mixed culture of Dehalococcoides species is provided that has an ability to catalyze the complete dechlorination of polychlorinated ethenes such as PCE, TCE, cDCE, 1,1-DCE and vinyl chloride as well as halogenated ethanes such as 1,2-DCA and EDB. The mixed culture demonstrates the ability to achieve dechlorination even in the presence of high source concentrations of chlorinated ethenes.
    Type: Application
    Filed: May 7, 2008
    Publication date: November 12, 2009
    Applicants: Washington Savannah River Co, LLC, Clemson University Research Foundation
    Inventors: Christopher E. Bagwell, David L. Freedman, Robin Brigmon, William B. Bratt, Elizabeth A. Wood
  • Patent number: 7598751
    Abstract: Embodiments according to the present invention provide an Impedance-based Arc-Fault Determination Device (IADD) and method that, when attached to an electrical node on the power system and through observations on voltage, current and phase shift with a step load change, determine the effective Thevenin equivalent circuit or Norton equivalent circuit at the point of test. The device and method determine the expected bolted fault current at the test location of interest, which enables calculation of incident energy and the assignment of a flash-hazard risk category.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: October 6, 2009
    Assignees: Clemson University Research Foundation, Duke Energy Carolinas, LLC
    Inventors: Edward Randolph Collins, Jr., Timothy Lee Smith, Randall J. Emanuel
  • Patent number: 7349731
    Abstract: The invention provides a means to produce reconstructed refractive index spatial maps that reveal and allow visual separation of normal soft tissue and certain types of tumors. Detector fiber optic bundles positioned on the surface of a soft tissue organ receive and transmit scattered light data, from light in the near-infrared portion of the spectrum delivered to the surface of the organ by separate fiber optic bundles to a computer. Based on an established grid and certain assumed values, the data are analyzed by means of a complex algorithm to produce calculated refractive index values. Through iteration, the values are recalculated to minimize the difference between the observed scattering and calculated values to yield a stable map indicating spatial variation in refractive index and such variation in the form of displayed images indicates the presence of tumors in normal soft tissue.
    Type: Grant
    Filed: May 29, 2003
    Date of Patent: March 25, 2008
    Assignee: Clemson University Research Foundation
    Inventor: Huabei Jiang
  • Patent number: 7252834
    Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: August 7, 2007
    Assignee: Clemson University Research Foundation (CURF)
    Inventors: Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu
  • Patent number: 6761957
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: July 13, 2004
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6617025
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: September 9, 2003
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6610402
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: August 26, 2003
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6605349
    Abstract: A deformable, shrinkable fiber that is dimensionally stable at normal body temperatures of approximately 37° C. in the dry state, but is dimensionally unstable (i.e. shrinks and distorts) when wet at the same temperature. The fiber comprises a fiber forming polymer that has a dry glass transition temperature (“dry Tg”) of greater than or equal to 42° C. and a wet glass transition temperature (“wet Tg”) of less than or equal to 32° C. A method of making said fiber and absorbent article(s) made therefrom are also disclosed.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: August 12, 2003
    Assignee: Clemson University Research Foundation
    Inventor: Bobby Mal Phillips
  • Publication number: 20030114068
    Abstract: An article of manufacture particularly suitable as wallboard, the article comprising a bonded nonwoven structure sandwiched between two layers of paper, wherein the bonded nonwoven structure comprises a binder and a load-bearing fiber wherein the load-bearing fiber has a shape factor between about 2 and 6, a short range distortion factor (SRDF) between about 5 and 70, a long range distortion factor (LRDF) between about 0.1 and 0.6, and a denier per filament (dpf) between about 3 and 200. A method of making the article is also disclosed.
    Type: Application
    Filed: December 13, 2002
    Publication date: June 19, 2003
    Applicant: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Leron Ronnie Dean
  • Publication number: 20030044601
    Abstract: A deformable, shrinkable fiber that is dimensionally stable at normal body temperatures of approximately 37° C. in the dry state, but is dimensionally unstable (i.e. shrinks and distorts) when wet at the same temperature. The fiber comprises a fiber forming polymer that has a dry glass transition temperature (“dry Tg”) of greater than or equal to 42° C. and a wet glass transition temperature (“wet Tg”) of less than or equal to 32° C. A method of making said fiber and absorbent article(s) made therefrom are also disclosed.
    Type: Application
    Filed: August 19, 2002
    Publication date: March 6, 2003
    Applicant: Clemson University Research Foundation
    Inventor: Bobby Mal Phillips
  • Patent number: 6509093
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: January 21, 2003
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6497955
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: December 24, 2002
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6495256
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: December 17, 2002
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6492023
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: December 10, 2002
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6468653
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: October 22, 2002
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6465096
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: October 15, 2002
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia
  • Patent number: 6451428
    Abstract: The ability to transport body liquids in consumer products such as diapers, incontinents and feminine napkins is a key factor in their performance. This invention is designed to provide specific high fluxes (volume of liquid/(time*mass of polymer) of aqueous liquids in designated directions using bundles of new specially designed fibers. The key factors for the bundles are a high specific adhesion for the liquid of interest, a high specific volume of the bundle itself, and alignment of the fibers within the bundle. The invention includes novel liquid acquisition/distribution systems and absorbent products that include a liquid acquisition/distribution system which may incorporate the novel bundles of fibers.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: September 17, 2002
    Assignee: Clemson University Research Foundation
    Inventors: Bobby Mal Phillips, Jackson Lee Nelson, Shriram Bagrodia