Patents Assigned to Clemson University Research Foundation (CURF)
  • Publication number: 20190190251
    Abstract: An improved DC circuit breaker is provided for automatically detecting and isolating a fault between a source and a ground. The DC circuit breaker comprises at least one switch, in electrical series with a first inductor between the source and a load, and a second inductor magnetically coupled to the first inductor wherein a first side of the second inductor is electrically connected to the load and a second side of the second inductor is grounded through a capacitor.
    Type: Application
    Filed: February 13, 2019
    Publication date: June 20, 2019
    Applicant: Clemson University Research Foundation (CURF)
    Inventor: Keith A. Corzine
  • Patent number: 9072761
    Abstract: Disclosed herein are compounds, compositions and methods related to viral inhibition. In some forms, the compounds, compositions and methods are related to binding RNA.
    Type: Grant
    Filed: August 16, 2010
    Date of Patent: July 7, 2015
    Assignee: Clemson University Research Foundation (CURF)
    Inventors: Dev P. Arya, Nihar Ranjan, Sunil Kumar
  • Patent number: 8435553
    Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: May 7, 2013
    Assignee: Clemson University Research Foundation (CURF)
    Inventors: Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu
  • Patent number: 8100961
    Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: January 24, 2012
    Assignee: Clemson University Research Foundation (CURF)
    Inventors: Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu
  • Publication number: 20110046982
    Abstract: Disclosed herein are compounds, compositions and methods related to viral inhibition. In some forms, the compounds, compositions and methods are related to binding RNA.
    Type: Application
    Filed: August 16, 2010
    Publication date: February 24, 2011
    Applicant: CLEMSON UNIVERSITY RESEARCH FOUNDATION (CURF)
    Inventors: Dev P. Arya, Nihar Ranjan, Sunil Kumar
  • Patent number: 7252834
    Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: August 7, 2007
    Assignee: Clemson University Research Foundation (CURF)
    Inventors: Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu