Patents Assigned to Clevexel Pharma
  • FREEZE-DRIED POWDER CONTAINING 2-[(3-AMINOPROPYL)AMINO]ETHANETHIOL AND ITS USE FOR PREPARING A THERMOGEL
    Publication number: 20230000801
    Abstract: A freeze-dried powder for preparing a thermogel including: from 1% to 35% of 2-[(3-aminopropyl)amino]ethanethiol or one of its pharmaceutically acceptable salt; from 40% to 85% of one or more poloxamer; and from 0.1% to 20% of one or more carbohydrate compound.
    Type: Application
    Filed: November 24, 2020
    Publication date: January 5, 2023
    Applicants: CLEVEXEL PHARMA, INSTITUT GUSTAVE ROUSSY, UNIVERSITE PARIS-SACLAY
    Inventors: Denis BRICOUT, Xiuping WANG-ZHANG, Eric DEUTSCH, Céline CLEMENSON
  • Process for the preparation of freeze-dried 2-[(3-aminopropyl)amino] ethanethiol formulation
    Patent number: 11021442
    Abstract: A process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol including the following steps: a) the reaction of a solution of amifostine with a strong acid, to obtain a solution of 2-[(3-aminopropyl)amino]ethanethiol, and b) the freeze-drying of the solution of 2-[(3-aminopropyl)amino]ethanethiol, with or without addition of excipients.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: June 1, 2021
    Assignees: CLEVEXEL PHARMA, INSTITUT GUSTAVE ROUSSY
    Inventors: Xiuping Wang-Zhang, Perrine Pivette, Karine Gonzalez, Eric Deutsch, Céline Clemenson
  • PROCESS FOR THE PREPARATION OF FREEZE-DRIED 2-[(3-AMINOPROPYL)AMINO]ETHANETHIOL FORMULATION
    Publication number: 20200239414
    Abstract: A process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol including the following steps: a) the reaction of a solution of amifostine with a strong acid, to obtain a solution of 2-[(3-aminopropyl)amino]ethanethiol, and b) the freeze-drying of the solution of 2-[(3-aminopropyl)amino]ethanethiol, with or without addition of excipients.
    Type: Application
    Filed: November 29, 2017
    Publication date: July 30, 2020
    Applicants: CLEVEXEL PHARMA, INSTITUT GUSTAVE ROUSSY
    Inventors: Xiuping WANG-ZHANG, Perrine PIVETTE, Karine GONZALEZ, Eric DEUTSCH, Céline CLEMENSON
  • Compositions and methods for modulating a kinase
    Patent number: 8937065
    Abstract: The invention relates to compounds and methods for modulating one or more components of a kinase signaling cascade.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: January 20, 2015
    Assignee: Clevexel Pharma
    Inventors: Oren M. Becker, Itai Bloch, Efrat Ben-Zeev, Alina Shitrit, Avihai Yacovan, Sharon Gazal, Vered Behar, Alexander Konson, Nili Schutz, Sima Mirilashvili, Gali Golan