Abstract: Aspects of the present disclosure are directed to systems, methods, and computer readable media for configuring generation of digital therapeutic content for provision. The system can receive a text input including one or more parameters identifying an audience and at least one domain. The system can identify content items generated by corresponding generative transformer models each using a prompt created based on the text input. The system can select, from a set of risk models for the domains, at least one risk model corresponding to the at least one domain. The system can apply the at least one risk model to each content item of the set of content items to determine a risk score. The system can select a content item based on the risk score of the content item. The system can present the content item including the respective digital therapeutic content.

Abstract: Aspects of the present disclosure are directed to systems, methods, and computer readable media for regulating digital therapeutic content for provision. A computing system may identify a digital therapeutic content to be provided via a network. The computing system may apply the digital therapeutic content to a machine learning (ML) model having a set of weights. The computing system may determine, from applying the digital therapeutic content to the ML model, an indication as of one of compliance or non-compliance. The computing system may store, using one or more data structures, an association between the digital therapeutic content and the indication used to control provision of the digital therapeutic content via the network, by (i) restricting the digital therapeutic content from provision responsive to determining the indication of non-compliance and (ii) permitting the digital therapeutic content to be provided responsive to determining the indication of compliance.

Abstract: Aspects of the present disclosure are directed to systems, methods, and computer readable media for regulating digital therapeutic content for provision. A computing system may identify a digital therapeutic content to be provided via a network. The computing system may apply the digital therapeutic content to a machine learning (ML) model having a set of weights. The computing system may determine, from applying the digital therapeutic content to the ML model, an indication as of one of compliance or non-compliance. The computing system may store, using one or more data structures, an association between the digital therapeutic content and the indication used to control provision of the digital therapeutic content via the network, by (i) restricting the digital therapeutic content from provision responsive to determining the indication of non-compliance and (ii) permitting the digital therapeutic content to be provided responsive to determining the indication of compliance.

Abstract: Aspects of the present disclosure are directed to systems, methods, and computer readable media for executing actions for events associated with use of applications. A computing system can identify free text associated with an application to be evaluated for at least one of a plurality of events associated with a use of the application. The computing system can apply the free text to a machine learning (ML) architecture. The computing system can determine, based on applying the free text to the ML architecture, a value indicating a likelihood of occurrence of an event associated with the use of the application. The computing system can provide to a generative ML model, a model input based on the free text and the value, to obtain data for an electronic document characterizing the event. The computing system can execute an action using the data for the electronic document.

Abstract: Aspects of the present disclosure are directed to systems, methods, and computer readable media for generating messages targeted to address conditions in users. A computing system may identify (i) a condition of a user to be addressed and (ii) one or more parameters defining messages to be presented via an application towards achieving an endpoint associated with the condition for the user. The computing system may generate a prompt using the condition and the one or more parameters in accordance with a template. The computing system may apply the prompt to a generative model to output a message identifying at least one activity toward achieving the endpoint. The generative model may be trained using a corpus. The computing system may provide, the message for presentation to prompt the user to perform the activity via the application towards achieving the endpoint to address the condition.

Abstract: Provided herein are systems and methods for presenting interactive sessions to address functional impairment in users related to a disease or disorder. A computing device may provide a first session for a cognitive training layer associated with a skill. The computing system may provide a second session for a virtual functional training layer for the user to apply the skill in virtual settings. The computing system may provide a third session for a functional training layer for the user to perform an activity to apply the skill. The efficacy of the medication that the user is taking to address the disease or disorder may be increased.

Abstract: Presented herein are systems and methods of secure transmissions of data packets to remote devices in networked environments. A server can establish a data connection over a network with an application executing on a client device associated with a user. The server can identify, for the user of the client device, (i) a plurality of messages to transmit to the client device for presentation via the application and (ii) a plurality of times at which to transmit the messages. The server can transmit, via the data connection to the client device, a first message at a first time. The server can receive, via the data connection from the client device, response data packets identifying an event detected responsive to the presentation of the first message via the application. The server can modify, using the one or more response data packets, a second time for transmission of a second message.

Abstract: Provided herein are systems and methods for presenting multimodal stimulus to address symptoms associated with conditions. A server may identify a first visual stimulus associated with a condition and a second visual stimulus. The server may present the first visual stimulus at least partially overlapped with the second visual stimulus, to direct the user to interact with the display. The service may detect a response identifying an interaction associated with one of the first or second visual stimulus. The server may generate an auditory stimulus to include one or more portions indicating feedback based on the response.

Abstract: Provided herein are systems and methods for providing training via visual elements for presentation to address maladaptive behavior in users. A server may identify a session defining a plurality of tasks for a user to be performed using at least one hand of the user holding a display to address a propensity for behavior associated with a condition of the user. The server may provide a first indication to perform a first task using the at least one hand. The server may provide, subsequent to the first task, a second indication to perform a second task using the at least one hand. The server may provide, subsequent to the second task, a third indication to perform a third task using the at least one hand. The user may be administered with an effective amount of a medication at least partially concurrently with the performance of the tasks.

Abstract: A method that includes receiving patient-generated event data over a network from a patient device associated with a patient having an active digital therapy prescription for treating an underlying disease or disorder. The patient-generated event data is encrypted by the patient device and includes at least one timestamped event related to the active digital therapy prescription. In response to receiving the patient-generated event data, the method includes decrypting, anonymizing, and storing the anonymized patient-generated event data on memory hardware. The method further includes receiving a patient record request over the network from a healthcare provider (HCP) system that requests the patient-generated event data and includes an authentication token. In response to receiving the patient record request, the method includes retrieving and encrypting the anonymized patient-generated event data from the memory hardware using the authentication token.

Abstract: The present disclosure discusses system and methods for improving the efficiency of a remote computing device. The system and methods include generate a profile and delivery schedule for the remote computing device. The system can dynamically update the delivery schedule of future requests the system transmits to the remote computing device based on responses to current request.

Abstract: Provided is a system for measuring and assessing intra-ocular pressure (IOP). The system comprises a processor, a memory, a camera, and instructions written on the memory. The instructions when executed by the processor may cause the system to: capture an image of a user's eye; convert the image to a three-dimensional image; analyze the three-dimensional image; and calculate an IOP measurement.

Abstract: A computer implemented method for increasing mobile application user engagement in a remote computing environment is provided. The method includes presenting a first popup window to a user including a first plurality of action buttons, a first of the first plurality of action buttons causing a change to a first attribute category to a first instantiation, and a second of the first plurality of action buttons causing a change to a second attribute category to a second instantiation, the first attribute category and the second attribute category comprising a type of attribute category of a second popup window; and subsequent to the presenting the first popup window to the user, presenting the second popup window to the user including a first instantiation if the first of the first plurality of action buttons was selected, and a second instantiation if the second of the first plurality of action buttons was selected.

Abstract: Provided herein are systems and methods of managing access to data associated with trials for digital therapeutics on participants. A server can maintain a data storage for a plurality of phases associated with a trial for a digital therapeutic on participants. The data storage may include (i) a first portion of a plurality of datasets from the plurality of participants from one or more of the plurality of phases of the trial, and (ii) a second portion of the plurality of datasets from the digital therapeutics in at least one of the plurality of phases of the trial. The server can receive from a user device, a request identifying a phase of the plurality of phases for which the plurality of datasets is to be accessed. The server can select a corresponding portion of the plurality of datasets based on the request to provide the user device.

Abstract: Provided herein are systems and methods of controlling the transmission of messages in a networked environment. A server can send a set of instructions to a user device associated with a user, each of the instructions to present a message in at least one of a set of variants. The server can receive a set of responses corresponding to the instructions, each of the responses by the user to a respective presentation of the message in at least one of the variants. The server can determine a respective performance measure of the message in each variant using the responses and can update a selection model responsive to the responses. The server can select variant from the based on the performance measure for the variant. The server can transmit a second instruction to the user device associated with the user to present the message in the selected variant.

Abstract: Presented herein are systems and methods for generating user interfaces based on conditions associated with users. A computing system can provide a first user interface comprising a first plurality of user interface elements to present first digital therapeutic content to a user. The first user interface can address a plurality of conditions. The computing system can identify a condition to be addressed in the user using data associated with the user. The computing system can generate a second user interface to include (i) at least one of the first plurality of user interface element and (ii) a second plurality of user interface elements to present second digital therapeutic content to address the condition. The computing system can provide the second user interface. The provision of the first and second digital therapeutic content can improve the efficacy of the medication taken by the user to address the condition.

Abstract: Presented herein are systems and methods of controlling access to user interfaces. A computing system can identify a plurality of user interfaces to present digital therapeutic content to a user to address a condition using one or more of the plurality of user interfaces. The computing system can provide, to a user device associated with the user over a time window, access to a subset of the plurality of user interfaces to present a corresponding portion of the digital therapeutic content to the user. The computing system can determine that interactions by the user satisfy a criterion based on data from the user device. The computing system can provide, to the user device, access to the plurality of user interfaces to present an entirety of the digital therapeutic content to the user, responsive to determining that the interactions satisfy the criterion.

Abstract: Aspects of the present disclosure are directed to systems, methods, and computer readable media for configuring generation of digital therapeutic content for provision. The system can receive a text input including one or more parameters identifying an audience and at least one domain. The system can identify content items generated by corresponding generative transformer models each using a prompt created based on the text input. The system can select, from a set of risk models for the domains, at least one risk model corresponding to the at least one domain. The system can apply the at least one risk model to each content item of the set of content items to determine a risk score. The system can select a content item based on the risk score of the content item. The system can present the content item including the respective digital therapeutic content.

Abstract: The present disclosure discusses system and methods for improving the efficiency of a remote computing device. The system and methods include generate a profile and delivery schedule for the remote computing device. The system can dynamically update the delivery schedule of future requests the system transmits to the remote computing device based on responses to current request.