Patents Assigned to Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.)
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Publication number: 20210246491Abstract: The present disclosure relates to methods and devices for amplifying a plurality of targets in a single PCR run while distinguishing between clinically relevant amplification and amplification from other sources such as from background contamination. The methods and devices further enable discrimination between gram-positive, gram-negative and fungal infections as wells as identify antimicrobial resistance genes. When applying the methods and devices of the invention, the species or genus of an infection(s), and genus of a fungal co-infection(s) or category of bacterial (gram-positive or negative) co-infection(s) are identified. Species identification of co-infections can also be achieved. Further, when applying the methods and devices of the invention, organisms which are likely to be contaminating organisms from a blood draw are identified.Type: ApplicationFiled: April 28, 2021Publication date: August 12, 2021Applicant: Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.)Inventors: Lisa Lynn Freeman-Cook, Christine J. Shaw, Milena Iacobelli Martinez, Anna Maria Al-Khouri, Bradley Adam Brown, John Jay Harvey, Michael Thomas Nguyen
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Publication number: 20200332346Abstract: The present disclosure relates to methods and devices for amplifying a plurality of targets in a single PCR run while distinguishing between clinically relevant amplification and amplification from other sources such as from background contamination. The methods and devices further enable discrimination between gram-positive, gram-negative and fungal infections as wells as identify antimicrobial resistance genes. When applying the methods and devices of the invention, the species or genus of an infection(s), and genus of a fungal co-infection(s) or category of bacterial (gram-positive or negative) co-infection(s) are identified. Species identification of co-infections can also be achieved. Further, when applying the methods and devices of the invention, organisms which are likely to be contaminating organisms from a blood draw are identified.Type: ApplicationFiled: April 24, 2020Publication date: October 22, 2020Applicant: Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.)Inventors: Lisa Lynn Freeman-Cook, Christine J. Shaw, Milena Iacobelli Martinez, Anna Maria Al-Khouri, Bradley Adam Brown, John Jay Harvey
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Publication number: 20190185915Abstract: The present disclosure relates to methods and devices for amplifying a plurality of targets in a single PCR run while distinguishing between clinically relevant amplification and amplification from other sources such as from background contamination. The methods and devices further enable discrimination between gram-positive, gram-negative and fungal infections as wells as identify antimicrobial resistance genes. When applying the methods and devices of the invention, the species or genus of an infection(s), and genus of a fungal co-infection(s) or category of bacterial (gram-positive or negative) co-infection(s) are identified. Species identification of co-infections can also be achieved. Further, when applying the methods and devices of the invention, organisms which are likely to be contaminating organisms from a blood draw are identified.Type: ApplicationFiled: February 26, 2019Publication date: June 20, 2019Applicant: Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.)Inventors: Lisa Lynn Freeman-Cook, Christine J. Shaw, Milena Iacobelli Martinez, Anna Maria Al-Khouri, Bradley Adam Brown, John Jay Harvey
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Publication number: 20190062809Abstract: The present disclosure relates to methods and devices for amplifying a plurality of targets in a single PCR run while distinguishing between clinically relevant amplification and amplification from other sources such as from background contamination. The methods and devices further enable discrimination between gram-positive, gram-negative and fungal infections as wells as identify antimicrobial resistance genes. When applying the methods and devices of the invention, the species or genus of an infection(s), and genus of a fungal co-infection(s) or category of bacterial (gram-positive or negative) co-infection(s) are identified. Species identification of co-infections can also be achieved. Further, when applying the methods and devices of the invention, organisms which are likely to be contaminating organisms from a blood draw are identified.Type: ApplicationFiled: August 24, 2017Publication date: February 28, 2019Applicant: Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.)Inventors: Bradley Adam Brown, Milena Iacobelli Martinez, Lisa Lynn Freeman--Cook, John Jay Harvey, Christin J. Shaw, Anna Maria Al-Khouri
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Publication number: 20190062803Abstract: The present disclosure relates to methods and devices for amplifying a plurality of targets in a single PCR run while distinguishing between clinically relevant amplification and amplification from other sources such as from background contamination. The methods and devices further enable discrimination between gram-positive, gram-negative and fungal infections as wells as identify antimicrobial resistance genes. When applying the methods and devices of the invention, the species or genus of an infection(s), and genus of a fungal co-infection(s) or category of bacterial (gram-positive or negative) co-infection(s) are identified. Species identification of co-infections can also be achieved. Further, when applying the methods and devices of the invention, organisms which are likely to be contaminating organisms from a blood draw are identified.Type: ApplicationFiled: August 3, 2018Publication date: February 28, 2019Applicant: Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.)Inventors: Bradley Adam Brown, Milena Iacobelli Martinez, Lisa Lynn Freeman-Cook, John Jay Harvey, Christine J. Shaw, Anna Maria Al-Khouri