Patents Assigned to Clinical Micro Sensors
  • Binding acceleration techniques for the detection of analytes
    Patent number: 6264825
    Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: July 24, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen D. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch
  • Detection of analytes using reorganization energy
    Patent number: 6248229
    Abstract: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, &lgr;, of an electron transfer process.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: June 19, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventor: Thomas J. Meade
  • AC methods for the detection of nucleic acids
    Patent number: 6232062
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: August 14, 1997
    Date of Patent: May 15, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon Faiz Kayyem, Stephen D. O'Connor
  • Methods of detecting nucleic acids using electrodes
    Patent number: 6221583
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: April 24, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon Faiz Kayyem, Stephen D. O'Connor, Michael Gozin, Changjun Yu, Thomas J. Meade
  • Electrodes linked via conductive oligomers to nucleic acids
    Patent number: 6096273
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: November 5, 1996
    Date of Patent: August 1, 2000
    Assignee: Clinical Micro Sensors
    Inventors: Jon F. Kayyem, Stephen D. O'Connor, Michael Gozin, Changjun Yu, Thomas J. Meade
  • Methods of attaching conductive oligomers to electrodes
    Patent number: 6090933
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: August 14, 1997
    Date of Patent: July 18, 2000
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon Faiz Kayyem, Stephen D. O'Connor, Michael Gozin, Changjun Yu, Thomas J. Meade
  • Cycling probe technology using electron transfer detection
    Patent number: 6063573
    Abstract: The invention relates to novel methods and compositions useful in Cycling Probe Technology (CPT) using electron transfer to detect target nucleic acid sequences.
    Type: Grant
    Filed: January 27, 1998
    Date of Patent: May 16, 2000
    Assignee: Clinical Micro Sensors, Inc.
    Inventor: Jon Faiz Kayyem
  • Detection of analytes using reorganization energy
    Patent number: 6013170
    Abstract: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, .lambda., of an electron transfer process.
    Type: Grant
    Filed: June 12, 1998
    Date of Patent: January 11, 2000
    Assignee: Clinical Micro Sensors, Inc.
    Inventor: Thomas J. Meade
  • Detection of analytes using reorganization energy
    Patent number: 6013459
    Abstract: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, .lambda., of an electron transfer process.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: January 11, 2000
    Assignee: Clinical Micro Sensors, Inc.
    Inventor: Thomas J. Meade