Patents Assigned to Clinical Reference Laboratory, Inc.
  • Publication number: 20230274414
    Abstract: A system and related methods are provided for processing a diagnostic test article, for example, one that is used for medical or substance testing. The system and methods combine a diagnostic test article with a software application that is integrated with each of a mobile communication device and a cloud-based network via an internet connection for achieving certain advantages and improvements over conventional point of use diagnostics.
    Type: Application
    Filed: May 7, 2023
    Publication date: August 31, 2023
    Applicant: Clinical Reference Laboratory, Inc.
    Inventor: Serhat Pala
  • Patent number: 11701660
    Abstract: A specimen sample collection device is disclosed, the device including: a base having a neck extending therefrom, a film-puncture element disposed within the neck, and one or more fluid ports extending through the base within the neck; a cap engaged with the neck, the cap comprising a film attached about an inner cylinder of the cap along a periphery thereof; wherein the film defines a buffer-containing cavity within the cap, and wherein the buffer-containing cavity is configured to hold a preservation buffer for preserving a sample stored within a collection reservoir of the device.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: July 18, 2023
    Assignee: Clinical Reference Laboratory, Inc.
    Inventor: Serhat Pala
  • Patent number: 11694326
    Abstract: A system and related methods are provided for processing a diagnostic test article, for example, one that is used for medical or substance testing. The system and methods combine a diagnostic test article with a software application that is integrated with each of a mobile communication device and a cloud-based network via an internet connection for achieving certain advantages and improvements over conventional point of use diagnostics.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: July 4, 2023
    Assignee: Clinical Reference Laboratory, Inc.
    Inventor: Serhat Pala
  • Patent number: 9738934
    Abstract: This invention relates to genetic markers of mental illness, e.g., schizophrenia (SZ), and methods of use thereof.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: August 22, 2017
    Assignee: Clinical Reference Laboratory, Inc.
    Inventors: Mark David Brennan, Timothy Lynn Ramsey
  • Publication number: 20160273042
    Abstract: Provided herein are genetic markers for predicting response to antipsychotic treatment. Genotyping of the disclosed SNPs can be used to predict response to antipsychotic drugs in patients suffering from schizophrenia. There is provided method of treating a subject with an antipsychotic medication comprising obtaining genetic information from the subject comprising the sequence of SNPs rs6923761, rs2300615, and rs1042044 to provide the GLP1 R Antipsychotic Response Phenotype (GARP) genetic signature of the subject; and administering an antipsychotic medication to the subject based on the GARP genetic signature of the subject.
    Type: Application
    Filed: November 6, 2014
    Publication date: September 22, 2016
    Applicant: Clinical Reference Laboratory, Inc.
    Inventors: Timothy RAMSEY, Mark BRENNAN
  • Publication number: 20130177994
    Abstract: Methods for the chiral separation and quantitative determination of the d- and l-enantiomers for amphetamine and methamphetamine in bodily fluids and tissues are provided. The method comprises providing a bodily fluid or tissue sample from a subject, extracting target analyte(s) from the sample, followed by eluting on a liquid chromatography column comprising a chiral stationary phase to yield an eluent, which is then analyzed for the presence of the analytes using a mass analyzer.
    Type: Application
    Filed: January 4, 2013
    Publication date: July 11, 2013
    Applicant: CLINICAL REFERENCE LABORATORY, INC.
    Inventor: Clinical Reference Laboratory, Inc.
  • Patent number: 4687665
    Abstract: A method is described for the production of large quantities of biologic which serves as an immunomodulator and also to decrease the concentration of serum cholesterol and triglycerides. In practice, an animal such as a goat is injected with a virus (preferably a normally immunosuppressive Parvovirus) and allowed to react to the virus for a period of time to generate the biologic in its blood serum; blood is then withdrawn from the animal and the serum fraction thereof, containing the desired biologic, can be used in fractionated or more highly purified form. Examples are also provided of use of the biologic as an immunostimulant and for reducing serum cholesterol and triglycerides.
    Type: Grant
    Filed: October 10, 1985
    Date of Patent: August 18, 1987
    Assignee: Clinical Reference Laboratory, Inc.
    Inventor: Robert L. Stout
  • Patent number: 4572834
    Abstract: A method is described for the production of large quantities of biologic which serves as an immunomodulator and also to decrease the concentration of serum cholesterol and triglycerides. In practice, an animal such as a goat is injected with a virus (preferably a normally immunosuppressive Parvovirus) and allowed to react to the virus for a period of time to generate the biologic in its blood serum; blood is then withdrawn from the animal and the serum fraction thereof, containing the desired biologic, can be used in fractionated or more highly purified form. Examples are also provided of use of the biologic as an immunostimulant and for reducing serum cholesterol and triglycerides.
    Type: Grant
    Filed: April 10, 1984
    Date of Patent: February 25, 1986
    Assignee: Clinical Reference Laboratory, Inc.
    Inventor: Robert L. Stout