Patents Assigned to Clinuvel Pharmaceuticals Limited
-
Patent number: 11622994Abstract: The present invention relates to a therapy for vitiligo. In particular the present invention provides a pharmaceutical composition comprising an alpha melanocyte stimulating hormone (alpha-MSH) analogue either alone, in combination with narrow band UVB and/or in combination with one or more corticosteroids, immunosuppressants, anti-inflammatory agents and/or photochemotherapeutic agents for the treatment or prevention of vitiligo.Type: GrantFiled: September 25, 2017Date of Patent: April 11, 2023Assignee: CLINUVEL PHARMACEUTICALS LIMITEDInventor: Philippe Wolgen
-
Patent number: 10857208Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.Type: GrantFiled: August 27, 2018Date of Patent: December 8, 2020Assignee: CLINUVEL PHARMACEUTICALS LIMITEDInventors: Michael John Kleinig, Thomas R. Tice, Jay K. Staas
-
Publication number: 20180360919Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.Type: ApplicationFiled: August 27, 2018Publication date: December 20, 2018Applicant: Clinuvel Pharmaceuticals LimitedInventors: Michael John KLEINIG, Thomas R. TICE, Jay K. STAAS
-
Patent number: 10076555Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.Type: GrantFiled: April 21, 2016Date of Patent: September 18, 2018Assignee: Clinuvel Pharmaceuticals LimitedInventors: Michael John Kleinig, Thomas R. Tice, Jay K. Staas
-
Patent number: 9801924Abstract: The present invention relates to a therapy for vitiligo. In particular the present invention provides a pharmaceutical composition comprising an alpha melanocyte stimulating hormone (alpha-MSH) analog either alone, in combination with narrow band UVB and/or in combination with one or more corticosteroids, immunosuppressants, anti-inflammatory agents and/or photochemotherapeutic agents for the treatment or prevention of vitiligo.Type: GrantFiled: March 13, 2013Date of Patent: October 31, 2017Assignee: Clinuvel Pharmaceuticals LimitedInventor: Philippe Wolgen
-
Publication number: 20160235819Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.Type: ApplicationFiled: April 21, 2016Publication date: August 18, 2016Applicant: Clinuvel Pharmaceuticals LimitedInventors: Michael John KLEINIG, Thomas R. TICE, Jay K. STAAS
-
Patent number: 9345911Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.Type: GrantFiled: February 11, 2005Date of Patent: May 24, 2016Assignee: Clinuvel Pharmaceuticals LimitedInventors: Michael John Kleinig, Thomas R. Tice, Jay K. Staas
-
Patent number: 8569234Abstract: Described herein are compositions comprising an alpha-MSH analogue and a transdermal delivery system and methods for inducing melanogenesis and/or preventing UV radiation-induced skin damage in a subject by topical administration of these compositions.Type: GrantFiled: October 7, 2005Date of Patent: October 29, 2013Assignee: Clinuvel Pharmaceuticals LimitedInventors: Michael John Kleinig, Kenneth B. Kirby, Berno I. Pettersson, Jr.
-
Publication number: 20130203670Abstract: The present invention relates to a therapy for vitiligo. In particular the present invention provides a pharmaceutical composition comprising an alpha melanocyte stimulating hormone (alpha-MSH) analogue either alone, in combination with narrow band UVB and/or in combination with one or more corticosteroids, immunosuppressants, anti-inflammatory agents and/or photochemotherapeutic agents for the treatment or prevention of vitiligo.Type: ApplicationFiled: March 13, 2013Publication date: August 8, 2013Applicant: CLINUVEL PHARMACEUTICALS LIMITEDInventor: Clinuvel Pharmaceuticals Limited
-
Patent number: 8334265Abstract: This invention relates to a method for prophylactic or therapeutic treatment of photodermatoses that are caused or exacerbated by or associated with UVR exposure in a subject, particularly a human subject, which comprises the step of administering to said subject an amount of an alpha-MSH analogue effective to reduce the photosensitivity of the skin of the subject.Type: GrantFiled: August 31, 2007Date of Patent: December 18, 2012Assignee: Clinuvel Pharmaceuticals LimitedInventor: Philippe Wolgen
-
Publication number: 20110263508Abstract: Described herein are compositions comprising an alpha-MSH analogue and a transdermal delivery system and methods for inducing melanogenesis and/or preventing UV radiation-induced skin damage in a subject by topical administration of these compositions.Type: ApplicationFiled: October 7, 2005Publication date: October 27, 2011Applicant: Clinuvel Pharmaceuticals LimitedInventors: Michael John Kleinig, Kenneth B. Kirby, Berno I. Pettersson, JR.
-
Publication number: 20110130705Abstract: The present invention relates to a therapy for vitiligo. In particular the present invention provides a pharmaceutical composition comprising an alpha melanocyte stimulating hormone (alpha-MSH) analogue either alone or in combination with one or more corticosteroids, immunosuppressants, anti-inflammatory agents and/or photochemotherapeutic agents for the treatment or prevention of vitiligo.Type: ApplicationFiled: March 27, 2009Publication date: June 2, 2011Applicant: Clinuvel Pharmaceuticals LimitedInventor: Philippe Wolgen
-
Patent number: 7745408Abstract: A method for inducing melanogenesis in a human subject having a melanocortin 1 receptor (MC1R) variant allele associated with loss of or diminished receptor function comprises administering to said subject an amount of an ?-melanocyte stimulating hormone (?-MSH) analogue effective to induce melanogenesis by the melanocytes in the skin or other epidermal tissue of the subject.Type: GrantFiled: November 23, 2004Date of Patent: June 29, 2010Assignee: Clinuvel Pharmaceuticals LimitedInventor: Stuart Michael Humphrey
-
Publication number: 20100113337Abstract: A method for treatment to reduce the incidence or rate of development of skin cancers and related conditions caused by or exacerbated by or associated with UVR-induced skin damage in an immuno-compromised subject, such as an organ transplant patient, comprises the step of administering to said subject an amount of an alpha-MSH analogue effective to protect the skin of the subject from UVR-induced skin damage.Type: ApplicationFiled: August 28, 2007Publication date: May 6, 2010Applicant: Clinuvel Pharmaceuticals LimitedInventor: Philippe Wolgen
-
Publication number: 20080305152Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.Type: ApplicationFiled: February 11, 2005Publication date: December 11, 2008Applicant: CLINUVEL PHARMACEUTICALS LIMITEDInventors: Michael John Kleinig, Thomas R. Tice, Jay K. Staas
-
Publication number: 20080004213Abstract: A method for inducing melanogenesis in a human subject having a melanocortin 1 receptor (MC1R) variant allele associated with loss of or diminished receptor function comprises administering to said subject an amount of an ?-melanocyte stimulating hormone (?-MSH) analogue effective to induce melanogenesis by the melanocytes in the skin or other epidermal tissue of the subject.Type: ApplicationFiled: November 23, 2004Publication date: January 3, 2008Applicant: Clinuvel Pharmaceuticals LimitedInventor: Stuart Humphrey