Abstract: A recombinant Mycobacterium strain co-expressing MIF and IL-7, and a composition containing the strain as an active ingredient are disclosed. The strain and the composition are suitable for preventing or treating cancer. The strain induces a maximized anticancer immune response by stably expressing MIF and IL-7 through a mycobacteria-derived replicable plasmid, such as a pMyong2 shuttle vector. Accordingly, the strain and the composition may be usefully used as an efficient anticancer live vaccine composition that induces multiple cellular and humoral immune responses through single administration of the recombinant strain.

Abstract: A a composition for prevention or treatment of a Staphylococcus aureus infectious disease and a composition for prevention or treatment of a thrombotic disorder caused by Staphylococcus aureus infection are disclosed. Cell lysis by 11 toxins of Staphylococcus aureus can be thoroughly inhibited by using the cross-reactivity of antibodies against Staphylococcus aureus toxins, even with a minimal combination of antigens. The composition can be used as an effective therapeutic composition that can comprehensively remove or alleviate comprehensive pathological conditions caused by infection, away from piecemeal amelioration of individual symptoms caused by Staphylococcus aureus infection, by inducing opsonophagocytosis and effectively controlling blood coagulation in infected individuals.