Patents Assigned to Clondiag GmbH
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Patent number: 8349616Abstract: A method for assaying a sample for each of multiple analysis is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones are disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone includes a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.Type: GrantFiled: November 22, 2007Date of Patent: January 8, 2013Assignee: Clondiag GmbHInventors: Torsten Schulz, Thomas Kaiser, Thomas Uhlig, Klaus Peter Möbius, Alexander Von Schenk Zu Schweinsberg
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Publication number: 20120321518Abstract: The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.Type: ApplicationFiled: August 28, 2012Publication date: December 20, 2012Applicant: CLONDIAG GMBHInventors: Eugen ERMANTRAUT, Torsten Schulz, Thomas Ellinger, Daniel Weicherding
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Patent number: 8278113Abstract: The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.Type: GrantFiled: July 14, 2009Date of Patent: October 2, 2012Assignee: Clondiag GmbHInventors: Eugen Ermantraut, Torsten Schulz, Thomas Ellinger, Daniel Weicherding
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Patent number: 8040494Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface.Type: GrantFiled: November 6, 2006Date of Patent: October 18, 2011Assignee: Clondiag GmbHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20110071038Abstract: The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.Type: ApplicationFiled: July 14, 2009Publication date: March 24, 2011Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Torsten Schulz, Thomas Ellinger, Daniel Weicherding
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Publication number: 20110014606Abstract: A device comprising a rigid substrate, a flexible cover element at least partially covering the substrate, a first structure formed in the substrate, adapted for accommodating liquids and adapted for releasing contents of one or more cells, spores, or viruses, the contents including the target molecules, a second structure formed in the substrate, adapted for accommodating liquids and comprising at least one binding member adapted for capturing the target molecules and for determining a value indicative of the presence and/or amount of the target molecules, a micro fluidic network interconnecting at least the first structure and the second structure, and an actuator member adapted for effecting a fluid flow between the first structure and the second structure by pressing the flexible cover element against the substrate to selectively close a portion of the micro fluidic network.Type: ApplicationFiled: November 6, 2007Publication date: January 20, 2011Applicant: CLONDIAG GMBHInventors: Katrin Steinmetzer, Eugen Ermantraut, Torsten Schulz, Thomas Kaiser
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Publication number: 20100179068Abstract: A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.Type: ApplicationFiled: May 5, 2008Publication date: July 15, 2010Applicant: CLONDIAG GMBHInventors: Thomas Kaiser, Klaus Peter Möbius, Torsten Schulz, Thomas Uhlig, Alexander Von Schenk Zu Schweinsberg, Eugen Ermantraut, Jens Tuchscheerer
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Publication number: 20100092683Abstract: A dispenser device (100) for dispensing a substance (101) onto a substrate (102), the dispenser device (100) comprising a gripper unit (103) adapted for gripping a container (104) including the substance (101), a first motion mechanism (116, 117) adapted for moving the gripper unit (103) and the substrate (102) relative to each other within a planar region (106), and a second motion mechanism (115, 201 and 209) adapted for moving the gripper unit (103) and the substrate (102) relative to each other in a direction (108) essentially perpendicular to the planar region (106) to thereby dispense the substance (101) to a surface portion (109) of the substrate (102), wherein the first motion mechanism (115) and the second motion mechanism (116, 117) are decoupled from one another.Type: ApplicationFiled: September 24, 2007Publication date: April 15, 2010Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Torsten Schulz, Jaochim Fischer, Daniel Weicherding, Siegfried Poser, Matthias Kirst
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Publication number: 20090082219Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.Type: ApplicationFiled: November 6, 2006Publication date: March 26, 2009Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
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Publication number: 20090079963Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface.Type: ApplicationFiled: November 6, 2006Publication date: March 26, 2009Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Patent number: D629907Type: GrantFiled: May 27, 2009Date of Patent: December 28, 2010Assignee: Clondiag GmbHInventors: Horst Boessneck, Eugen Ermantraut, Thomas Kaiser, Torsten Schulz
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Patent number: D633209Type: GrantFiled: May 27, 2009Date of Patent: February 22, 2011Assignee: Clondiag GmbHInventors: Horst Boessneck, Eugen Ermantraut, Thomas Kaiser, Torsten Schulz
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Patent number: D641477Type: GrantFiled: November 30, 2010Date of Patent: July 12, 2011Assignee: Clondiag GmbHInventors: Horst Boessneck, Eugen Ermantraut, Thomas Kaiser, Torsten Schulz