Patents Assigned to CLORADO STATE UNIVERSITY RESEARCH FOUNDATION
  • Biosynthetic Pathway for Heterologous Expression of a Nonribosomal Peptide Synthetase Drug and Analogs
    Publication number: 20130095533
    Abstract: The present invention is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention also discloses polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS derived drug.
    Type: Application
    Filed: April 15, 2011
    Publication date: April 18, 2013
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, CLORADO STATE UNIVERSITY RESEARCH FOUNDATION, ALLEGHENY-SINGER RESEARCH INSTITUTE
    Inventors: David H. Sherman, Garth D. Ehrlich, Benjamin Janto, Robert M. Williams, Christopher M. Rath