Abstract: Crosslinked biocompatible compositions comprising an ionically crosslinked component and a covalently crosslinked component for encapsulating biologics are disclosed. In accordance with the present invention, also disclosed are crosslinkable biocompatible mixtures comprising an ionically crosslinkable component and a covalently crosslinkable component. Methods for encapsulating biologics with the crosslinked and crosslinkable biocompatible compositions are provided. Also, retrievable macrocapsules for encapsulating microcapsules or biologics are disclosed.
Type:
Grant
Filed:
April 8, 1992
Date of Patent:
August 2, 1994
Assignee:
Clover Consolidated, Ltd.
Inventors:
Neil P. Desai, Patrick Soon-Shiong, Paul A. Sandford, Roswitha E. Heintz