Abstract: A tablet including high dosage of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one camsylate salt has been disclosed.
Abstract: A tablet including high dosage of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one camsylate salt has been disclosed.
Abstract: The subject invention relates to determining the presence and level of hENT1 expression in tumor tissue that is appropriate for gemcitabine therapy, and more importantly, the level of hENT1 expression that signifies that treatment with a gemcitabine derivative is a more appropriate strategy.
Type:
Application
Filed:
August 2, 2012
Publication date:
May 9, 2013
Applicants:
VENTANA MEDICAL SYSTEMS, INC., CLOVIS ONCOLOGY, INC.
Inventors:
Jeffrey Dean Isaacson, Mical Raponi, James Ranger-Moore, Eric L. Powell
Abstract: The subject invention relates to determining the presence and level of hENT1 expression in tumor tissue that is appropriate for gemcitabine therapy, and more importantly, the level of hENT1 expression that signifies that treatment with a gemcitabine derivative is a more appropriate strategy.
Type:
Application
Filed:
August 2, 2012
Publication date:
May 9, 2013
Applicants:
VENTANA MEDICAL SYSTEMS, INC., CLOVIS ONCOLOGY, INC.
Inventors:
Jeffrey Dean Isaacson, Mical Raponi, James Ranger-Moore, Eric L. Powell