Abstract: A device for cell culture, in particular of neuronal cells, including: a substrate defining a first microfluidic chamber to be seeded with a first cell culture, and at least a second microfluidic chamber, a fluidic interconnection system connecting the first and second chambers and enabling cellular extensions, in particular axons, to extend from one chamber to the other, wherein the interconnection system of the device is made so as to promote the progression of at least one first type of cellular extension, the first and second types of extension being different either due to the microfluidic chamber from which they originate, or due to the type of cell of which they constitute an extension.
Abstract: A device for cell culture, in particular of neuronal cells, including: a substrate defining a first microfluidic chamber to be seeded with a first cell culture, and at least a second microfluidic chamber, a fluidic interconnection system connecting the first and second chambers and enabling cellular extensions, in particular axons, to extend from one chamber to the other, wherein the interconnection system of the device is made so as to promote the progression of at least one first type of cellular extension, the first and second types of extension being different either due to the microfluidic chamber from which they originate, or due to the type of cell of which they constitute an extension.
Type:
Application
Filed:
October 12, 2009
Publication date:
December 15, 2011
Applicants:
CNRS-DAE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), INSTITUT CURIE
Inventors:
Jean-Louis Viovy, Jean-Michel Peyrin, Bernard Brugg, Laure Saias, Paul Gougis, Maeva Vignes
Abstract: An integrated microsystem, comprising: a microchannel, a field generator to create a magnetic field in at least one first portion of the microchannel having a direction substantially collinear with the direction of flow in the portion of the microchannel, the magnetic field also presenting a gradient, wherein the microsystem additionally comprises a detection area in fluid connection with the microchannel,
Type:
Application
Filed:
October 12, 2009
Publication date:
September 1, 2011
Applicants:
CNRS-DAE, INSTITUT CURIE, UNIVERSITE PIERRE ET MARIE CURIE, FLUIGENT