Patents Assigned to COBIORES NV
  • Minimally toxic prodrugs
    Patent number: 10583194
    Abstract: The present invention relates to the field of oligopeptide prodrugs that are intended for the treatment of cancer. The selectivity of these prodrugs requires the presence of an (oligo)peptidic moiety and/or a protective capping group to ensure the prodrug stability in blood. It further in particular relates to the exemplary oligopeptidic moiety ALGP and to prodrugs comprising it. In particular it also relates to the capping group phosphonoacetyl and to prodrugs comprising this capping group.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: March 10, 2020
    Assignee: COBIORES NV
    Inventor: André Trouet