Abstract: This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.
Type:
Grant
Filed:
March 15, 2014
Date of Patent:
March 22, 2016
Assignee:
CoDa Technologies, Inc.
Inventors:
Anthony Phillips, David Eisenbud, Scott Bannan, David Pool, Grove Matsuoka, Tracey Sunderland, Bradford Duft