Patents Assigned to COGNATE THERAPEUTICS, INC.
  • Liver stromal cells for prevention and treatment of immune responses in transplantation
    Patent number: 9408876
    Abstract: The present invention encompasses methods and compositions for reducing an immune response to a transplant in a recipient by treating said recipient with an amount of liver stromal cells effective to reduce or inhibit host rejection of the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with liver stromal cells.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: August 9, 2016
    Assignee: Cognate Therapeutics, Inc.
    Inventor: Kevin R. McIntosh
  • Isolation and purification of hematopoietic stem cells from post-liposuction lipoaspirates
    Publication number: 20070274965
    Abstract: The present invention relates to a method of isolating hematopoietic stem cells from adipose tissue. The method yields a notably high number of CD34+, ALDHbr and/or ABCG2-expressing cells, comprising hematopoietic stem cells, permitting the use of the cells with no or minimal expansion.
    Type: Application
    Filed: January 8, 2007
    Publication date: November 29, 2007
    Applicant: COGNATE THERAPEUTICS, INC.
    Inventor: James Mitchell