Patents Assigned to Coherus Biosciences, Inc.
  • Stable aqueous formulations of adalimumab
    Patent number: 9682145
    Abstract: The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: June 20, 2017
    Assignee: Coherus Biosciences, Inc.
    Inventors: Mark Manning, Robert W. Payne
  • Stable aqueous formulations of etanercept
    Patent number: 9662396
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: May 30, 2017
    Assignee: Coherus Biosciences, Inc.
    Inventors: Mark Manning, Brian Murphy
  • Etanercept formulations stabilized with xylitol
    Patent number: 9393305
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: July 19, 2016
    Assignee: Coherus Biosciences, Inc.
    Inventors: Mark Manning, Brian Murphy
  • Stable aqueous formulations of adalimumab
    Patent number: 9382317
    Abstract: The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: July 5, 2016
    Assignee: Coherus Biosciences, Inc.
    Inventors: Mark Manning, Robert W. Payne
  • Stable aqueous formulations of adalimumab
    Patent number: 9346880
    Abstract: The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: May 24, 2016
    Assignee: COHERUS BIOSCIENCES, INC.
    Inventors: Mark Manning, Robert W. Payne
  • Stable aqueous formulations of adalimumab
    Patent number: 9340611
    Abstract: The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: May 17, 2016
    Assignee: Coherus Biosciences, Inc.
    Inventors: Mark Manning, Robert W. Payne
  • Stable aqueous formulations of adalimumab
    Patent number: 9340612
    Abstract: The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: May 17, 2016
    Assignee: Coherus Biosciences, Inc.
    Inventors: Mark Manning, Robert W. Payne
  • Etanercept formulations stabilized with combinations of sugars and polyols
    Patent number: 9302002
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: April 5, 2016
    Assignee: Coherus Biosciences, Inc.
    Inventors: Mark Manning, Brian Murphy
  • Protein Production Method
    Publication number: 20140296489
    Abstract: Production of etanercept using perfusion methods achieves attractive yields of properly folded protein. Desired temperature, feed media, titers and percent correctly folded protein are disclosed.
    Type: Application
    Filed: March 26, 2014
    Publication date: October 2, 2014
    Applicant: Coherus Biosciences, Inc.
    Inventors: Ela Puchacz, James Russell Grove
  • Stable Aqueous Formulations of Adalimumab
    Publication number: 20140186361
    Abstract: The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Application
    Filed: September 6, 2013
    Publication date: July 3, 2014
    Applicant: Coherus Biosciences, Inc.
    Inventors: Mark Manning, Robert W. Payne
  • CORRECTLY FOLDED ETANERCEPT IN HIGH PURITY AND EXCELLENT YIELD
    Publication number: 20140072560
    Abstract: A mixed mode chromatography method for separating correctly folded from incorrectly folded conformations of a given protein is provided. The method is highly effective in separating correctly folded etanercept from incorrectly folded etanercept and aggregates in commercially attractive yields capable of affording etanercept preparations having very high purity in terms of correctly folded etanercept versus incorrectly folded etanercept. The invention is further directed to protein preparations and formulations comprising correctly folded proteins obtained using the present methods, and methods of treatment using the high purity preparations obtained from the mixed mode method.
    Type: Application
    Filed: September 11, 2013
    Publication date: March 13, 2014
    Applicant: COHERUS BIOSCIENCES, INC.
    Inventors: Tsutomu Arakawa, Douglas Farrar
  • Etanercept Formulations Stabilized with Meglumine
    Publication number: 20130108634
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Application
    Filed: October 18, 2012
    Publication date: May 2, 2013
    Applicant: COHERUS BIOSCIENCES, INC.
    Inventor: COHERUS BIOSCIENCES, INC.
  • Etanercept Formulations Stabilized with Metal Ions
    Publication number: 20130108633
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Application
    Filed: October 18, 2012
    Publication date: May 2, 2013
    Applicant: COHERUS BIOSCIENCES, INC.
    Inventor: Coherus Biosciences, Inc.
  • Etanercept Formulations Stabilized with Amino Acids
    Publication number: 20130108632
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions stabilized with an amino acid and suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Application
    Filed: October 18, 2012
    Publication date: May 2, 2013
    Applicant: COHERUS BIOSCIENCES, INC.
    Inventor: Coherus Biosciences, Inc.
  • Etanercept Formulations Stabilized with Sodium Chloride
    Publication number: 20130101583
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Application
    Filed: October 18, 2012
    Publication date: April 25, 2013
    Applicant: Coherus Biosciences, Inc.
    Inventor: Coherus Biosciences, Inc.
  • Etanercept Formulations Stabilized with Combinations of Sugars and Polyols
    Publication number: 20130101640
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Application
    Filed: October 18, 2012
    Publication date: April 25, 2013
    Applicant: COHERUS BIOSCIENCES, INC.
    Inventor: COHERUS BIOSCIENCES, INC.
  • Etanercept Formulations Stabilized with Xylitol
    Publication number: 20130101584
    Abstract: The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
    Type: Application
    Filed: October 18, 2012
    Publication date: April 25, 2013
    Applicant: COHERUS BIOSCIENCES, INC.
    Inventor: COHERUS BIOSCIENCES, INC.